ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
DYT25 antibody, zgc:103521 antibody, 2610011C15Rik antibody, 9630020G10Rik antibody, AI843190 antibody, Galphaolf antibody, Gna10 antibody, Golf antibody, Olf antibody, RGD1305940 antibody, G protein subunit alpha L antibody, guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type antibody, guanine nucleotide binding protein, alpha stimulating, olfactory type antibody, GNAL antibody, gnal antibody, Gnal antibody
背景
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (e.g. adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein α, β and γ polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their α subunits, since these proteins bind and hydrolyze GTP, and most obviously regulate the activity of the best studied effectors. The Gs subfamily of Gα subunits includes two closely related proteins, Gα s and Gα olf, which, respectively, stimulate adenylate cyclase and mediate response to olfactory stimuli.Synonyms: Adenylate cyclase-stimulating G alpha protein olfactory type, GNAL, Guanine nucleotide-binding protein G(olf) subunit alpha