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GFRA4 抗体

GFRA4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317910
发货至: 中国
  • 抗原 See all GFRA4 抗体
    GFRA4 (GDNF Family Receptor alpha 4 (GFRA4))
    适用
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    宿主
    • 39
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    克隆类型
    • 41
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    多克隆
    标记
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    This GFRA4 antibody is un-conjugated
    应用范围
    • 27
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    Western Blotting (WB)
    特异性
    GFRα-4 antibody detects endogenous levels of GFRα-4 protein.(region surrounding Pro178)
    纯化方法
    Affinity chromatography
    Top Product
    Discover our top product GFRA4 Primary Antibody
  • 应用备注
    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    GFRA4 (GDNF Family Receptor alpha 4 (GFRA4))
    别名
    GFRA4 / GDNFR-alpha 4 (GFRA4 产品)
    别名
    zgc:171814 antibody, AW060733 antibody, G630015H18Rik antibody, GDNF family receptor alpha 4 antibody, GDNF family receptor alpha 4a antibody, glial cell line derived neurotrophic factor family receptor alpha 4 antibody, GFRA4 antibody, gfra4a antibody, Gfra4 antibody
    背景
    Glial cell line-derived neurotrophic factor (GDNF) and the related neurotrophic factor neurturin (NTN) are potent survival factors for central and peripheral neurons. Receptors for these factors include GFRα-1 (previously designated GDNFR-α), GFRα-2 (also designated RETL2), GFRα-3 and GFRα-4 (also known as persephin receptor). The receptors do not contain transmembrane domains and are attached to the cell membrane by glycosylphosphoinositol linkage. Binding of GDNF or NTN to one of these receptors leads to the activation of the tyrosine kinase Ret. GFRα-4 mediates the activation and GDNF-induced autophosphorylation of the RET receptor. It is mainly expressed in the adult thyroid gland, but lower levels may also be detected in fetal adrenal and thyroid glands.Synonyms: GDNF family receptor alpha-4, GDNF receptor alpha-4, GFR-alpha-4, Persephin receptor
    分子量
    approx. 30 kDa
    基因ID
    64096
    NCBI登录号
    NP_071422
    UniProt
    Q9GZZ7
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