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OXER1 抗体

OXER1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317873
发货至: 中国
  • 抗原 See all OXER1 抗体
    OXER1 (Oxoeicosanoid Receptor 1 (OXER1))
    适用
    • 25
    • 3
    • 2
    • 1
    • 1
    宿主
    • 22
    • 2
    • 1
    克隆类型
    • 25
    多克隆
    标记
    • 21
    • 2
    • 1
    • 1
    This OXER1 antibody is un-conjugated
    应用范围
    • 18
    • 13
    • 10
    • 7
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    TG1019 antibody detects endogenous levels of TG1019 protein.(region surrounding Arg251)
    纯化方法
    Affinity chromatography
    Top Product
    Discover our top product OXER1 Primary Antibody
  • 应用备注
    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    OXER1 (Oxoeicosanoid Receptor 1 (OXER1))
    别名
    Oxoeicosanoid Receptor 1 (OXER1 产品)
    别名
    GPCR antibody, GPR170 antibody, TG1019 antibody, oxoeicosanoid receptor 1 antibody, OXER1 antibody
    背景
    TG1019 is a G protein-coupled receptor that functions as a chemoattractant for eosinophils and neutrophils. TG1019 is expressed in various tissues except the brain, with the highest expression in liver, kidney, peripheral leukocyte, lung and spleen. TG1019 interacts with the protein OXE to form TG1019/OXE, a Gα i/o protein-coupled receptor. Signals from TG1019 are transduced via a Gα i/o protein to PLC/calcium, MEK/ERK and PI3K/Akt pathways. Signal transduction from TG1019 following stimulation with 5-oxo-6E,8Z,11Z,14Z eicosatetraenoic acid (5-oxo-ETE) induces intracellular calcium mobilization and rapid activation of MEK/ERK and PI3K/Akt pathways. TG1019 also may play a role in downregulating cAMP production.Synonyms: 5-oxo-ETE G-protein coupled receptor, GPR170, OXER1, R527, TG1019
    分子量
    approx. 46 kDa
    基因ID
    165140
    NCBI登录号
    NP_683765
    UniProt
    Q8TDS5
    途径
    cAMP Metabolic Process
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