ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
浓度
1,0 mg/mL
缓冲液
Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原
GPRC5A
(G Protein-Coupled Receptor, Family C, Group 5, Member A (GPRC5A))
GPCR5A antibody, RAI3 antibody, RAIG1 antibody, Rai3 antibody, Raig1 antibody, G protein-coupled receptor class C group 5 member A antibody, G protein-coupled receptor, family C, group 5, member A antibody, G protein-coupled receptor, class C, group 5, member A antibody, GPRC5A antibody, Gprc5a antibody
背景
Retinoic acid-induced protein 3 (RAI3) is a transmembrane G protein-coupled receptor that affects many essential biological processes including embryogenesis,cell growth, differentiation and apoptosis. RAI3 may also be involved in maintaining homeostasis of epithelial cells. Retinoic acid receptors directly regulate RAI3 during its transcription in embryonal carcinoma differentiation. RAI3 expression is upregulated in most tumor cell lines that express mutant p53, suggesting that p53 interacts with the promoter of RAI3 and represses its expression at the beginning of apoptosis. RAI3 is a potential molecular target for diagnosing breast cancer, selective suppression of signals from RAI3 may have a place in breast cancer treatments.Synonyms: G-protein coupled receptor C5A, GPCR5A, Orphan G-protein-coupling receptor PEIG-1, PEIG-1, RAIG1, Retinoic acid-induced gene 1 protein, Retinoic acid-induced protein 3