PTGER3 抗体
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- 抗原 See all PTGER3 抗体
- PTGER3 (Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PTGER3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of EP3 protein.(region surrounding Arg39)
- 纯化方法
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product PTGER3 Primary Antibody
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anti-Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) (AA 217-390) antibody
PTGER3 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) (N-Term) antibodyPTGER3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) (AA 2283-2414) antibodyPTGER3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) (AA 17-46), (N-Term) antibodyPTGER3 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB22525 unconjugated
anti-Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) (AA 1-49) antibodyPTGER3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) (C-Term) antibodyPTGER3 适用: 人 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) (Cytoplasmic Domain) antibodyPTGER3 适用: 人, 猴, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) (Cytoplasmic Domain) antibodyPTGER3 适用: 人, 小鼠, 大鼠, 马, 猴, 兔, Bat ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) (AA 1-388) antibodyPTGER3 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) (AA 1-50) antibodyPTGER3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/5000-1/10000. Western blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- PTGER3 (Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3))
- 别名
- PTGER3 (PTGER3 产品)
- 别名
- PTGER3 antibody, EP3 antibody, EP3-I antibody, EP3-II antibody, EP3-III antibody, EP3-IV antibody, EP3e antibody, PGE2-R antibody, PTGEREP3 antibody, Rep3 antibody, rEP3a antibody, rEP3b antibody, Pgerep3 antibody, Ptgerep3 antibody, prostaglandin E receptor 3 antibody, prostaglandin E receptor 3 L homeolog antibody, prostaglandin E receptor 3 (subtype EP3) antibody, PTGER3 antibody, ptger3.L antibody, Ptger3 antibody
- 背景
- Prostaglandin E2, a member of the autacoid family of lipid mediators, is a major renal cyclooxygenase product of arachidonic acid metabolism. Prostaglandin E2 binds to four G protein-coupled E-prostanoid receptors, designated EP1, EP2, EP3 and EP4. The expression and function of the prostaglandin E2 receptors have been highly characterized in kidney. EP1, which is predominantly expressed in the collecting duct, couples to Gq proteins to inhibit sodium absorption and increase in intracellular calcium, which act as second messengers. EP2 is coupled to Gs proteins, which stimulate adenylyl cyclase. EP2 has the lowest expression in kidney, but EP2 knockout mice exhibit saltsensitive hypertension, which suggests a role for EP2 in salt excretion. EP3, which is expressed in renal vessels, thick ascending limb and collecting duct, has at least six alternative splice variants that couple to Gi proteins to inhibit cAMP, which subsequently inhibit sodium and water transport. In uterus, EP3 induces the contraction of uterine smooth muscles. EP4 is expressed in glomerulus and collecting duct.Synonyms: EP3, EP3-II, EP3-III, PGE receptor EP3 subtype, PGE2 receptor EP3 subtype, PGE2-R, Prostaglandin E receptor 3, Prostaglandin E2 receptor EP3 subtype, Prostanoid EP3 receptor
- 分子量
- approx. 40 kDa
- 基因ID
- 5733
- NCBI登录号
- NP_001119516
- UniProt
- P43115
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