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CLCN6 抗体

CLCN6 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317827
发货至: 中国
  • 抗原 See all CLCN6 抗体
    CLCN6 (Chloride Channel, Voltage-Sensitive 6 (CLCN6))
    适用
    • 14
    • 7
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 13
    • 1
    克隆类型
    • 13
    • 1
    多克隆
    标记
    • 11
    • 1
    • 1
    • 1
    This CLCN6 antibody is un-conjugated
    应用范围
    • 10
    • 10
    • 2
    • 1
    Western Blotting (WB)
    特异性
    CLC-6 antibody detects endogenous levels of CLC-6 protein.(region surrounding Lys649)
    纯化方法
    Affinity chromatography
    Top Product
    Discover our top product CLCN6 Primary Antibody
  • 应用备注
    ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CLCN6 (Chloride Channel, Voltage-Sensitive 6 (CLCN6))
    别名
    CLCN6 (CLCN6 产品)
    别名
    CLC-6 antibody, AI850629 antibody, CLCN6 antibody, wu:fb95f01 antibody, DKFZp469B244 antibody, DKFZp469L0417 antibody, chloride voltage-gated channel 6 antibody, chloride channel, voltage-sensitive 6 antibody, chloride channel 6 antibody, chloride transport protein 6 antibody, CLCN6 antibody, Clcn6 antibody, clcn6 antibody, LOC579870 antibody
    背景
    The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport and maintain cellular volume. The genes encoding human CLC-1 through CLC-7 map to chromosomes 7, 3q26, 4q32, Xp22, Xp11, 1p36 and 16p13, respectively. CLC-1 is highly expressed in skeletal muscle. Mutations in the gene encoding CLC-1 lead to myotonia, an inheritable disorder characterized by muscle stiffness and renal salt wasting. CLC-2 is highly expressed in the epithelia of several organs including lung, which suggests CLC-2 may be a possible therapeutic target for cystic fibrosis. CLC-3 expression is particularly abundant in neuronal tissue, while CLC-4 expression is evident in skeletal and cardiac muscle as well as brain. Mutations in the gene encoding CLC-5 lead to Dent's disease, a renal disorder characterized by proteinuria and hypercalciuria. CLC-6 and CLC-7 are broadly expressed in several tissues including testes, kidney, brain and muscle.Synonyms: Chloride channel protein 6, Chloride transport protein 6, ClC-6, ClC6, KIAA0046
    分子量
    approx. 90 kDa
    基因ID
    1185
    NCBI登录号
    NP_001277
    UniProt
    P51797
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