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ARFIP1 抗体

ARFIP1 适用: 人, 大鼠, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317818
发货至: 中国
  • 抗原 See all ARFIP1 抗体
    ARFIP1 (ADP-Ribosylation Factor Interacting Protein 1 (ARFIP1))
    适用
    • 54
    • 17
    • 16
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 50
    • 4
    克隆类型
    • 52
    • 2
    多克隆
    标记
    • 23
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARFIP1 antibody is un-conjugated
    应用范围
    • 32
    • 23
    • 19
    • 13
    • 13
    • 10
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of Arfaptin-1 protein.(region surrounding Lys314)
    纯化方法
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product ARFIP1 Primary Antibody
  • 应用备注
    ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ARFIP1 (ADP-Ribosylation Factor Interacting Protein 1 (ARFIP1))
    别名
    Arfaptin-1 (ARFIP1 产品)
    别名
    arfip1 antibody, MGC53116 antibody, DKFZp469C2322 antibody, HSU52521 antibody, 2310030I10Rik antibody, AW123087 antibody, Arfaptin antibody, D3Ertd598e antibody, ADP ribosylation factor interacting protein 1 antibody, ADP ribosylation factor interacting protein 1 L homeolog antibody, Arfaptin-1 antibody, ADP-ribosylation factor interacting protein 1 antibody, ARFIP1 antibody, arfip1.L antibody, arfp1 antibody, Arfip1 antibody
    背景
    Arfaptin 1 is an ARF binding protein that inhibits PLD activation, vesicular trafficking and secretion. In the present report, we show that arfaptin 1 interacts with 'high speed' membranes independently of ARF. However, addition of myristoylated ARF3 (myrARF3) increases the association of arfaptin 1 with the membranes, suggesting that arfaptin 1 and ARF form a complex on the Golgi. Utilizing several deletion mutants of arfaptin 1 it is shown that the association of arfaptin 1 with myrARF3 is mediated via two binding sites on arfaptin 1. These two domains are needed for arfaptin 1 inhibition of PLD activation by myrARF3 in vitro.Synonyms: ADP-ribosylation factor-interacting protein 1, ARFIP1
    分子量
    approx. 40 kDa
    基因ID
    27236
    NCBI登录号
    NP_001020764
    UniProt
    P53367
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