GTPBP1 抗体
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- 抗原 See all GTPBP1 抗体
- GTPBP1 (GTP Binding Protein 1 (GTPBP1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GTPBP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 特异性
- GBP1 antibody detects endogenous levels of GBP1 protein.(region surrounding Glu99)
- 纯化方法
- Affinity chromatography
- Top Product
- Discover our top product GTPBP1 Primary Antibody
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anti-GTP Binding Protein 1 (GTPBP1) (AA 1-76) antibody
GTPBP1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1H1 unconjugated
anti-GTP Binding Protein 1 (GTPBP1) (AA 562-669) antibodyGTPBP1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GTP Binding Protein 1 (GTPBP1) (Internal Region) antibodyGTPBP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GTP Binding Protein 1 (GTPBP1) antibodyGTPBP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-GTP Binding Protein 1 (GTPBP1) (AA 1-76) antibodyGTPBP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-GTP Binding Protein 1 (GTPBP1) (AA 1-584) antibodyGTPBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-GTP Binding Protein 1 (GTPBP1) (AA 36-85) antibodyGTPBP1 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 小鸡, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-GTP Binding Protein 1 (GTPBP1) (AA 10-280) antibodyGTPBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- GTPBP1 (GTP Binding Protein 1 (GTPBP1))
- 别名
- GTP-Binding Protein 1 / GBP1 (GTPBP1 产品)
- 别名
- GP-1 antibody, GP1 antibody, HSPC018 antibody, AL022987 antibody, AW045683 antibody, C85212 antibody, Gtpbp antibody, cb858 antibody, wu:fb36e06 antibody, wu:fi39g05 antibody, zgc:66228 antibody, gtpbp1 antibody, GTP binding protein 1 antibody, GTP binding protein 1 S homeolog antibody, GTPBP1 antibody, Gtpbp1 antibody, gtpbp1 antibody, gtpbp1.S antibody
- 背景
- GBP1 (guanylate binding protein 1) is a 592 amino acid protein member of the GTPase protein family and is able to bind specifically to guanine nucleotides such as GMP, GDP and GTP. GMP is hydrolyzed to GTP in two consecutive cleavage step, both of which are carried out by GBP1. Localized to the cytoplasm, GBP1 is expressed in endothelial cells of the vascular system and is induced by IFN-γ during macrophage induction. GBP1 is thought to regulate the expression of MMP-1, which mediates the proliferation and invasiveness of endothelial cells. GBP1 plays a key role in regulating inflammatory cytokines and provides protection against vesicular stomatitis and encephalomyocarditis viruses. GBP1 expression is highly induced in the vessels of skin diseases such as psoriasis and Kaposi's sarcoma, making it a novel cellular activation marker that characterizes inflammatory cytokines of endothelial cells.Synonyms: Guanine nucleotide-binding protein 1, HuGBP-1, Interferon-induced guanylate-binding protein 1
- 分子量
- approx. 68 kDa
- 基因ID
- 2633
- NCBI登录号
- NP_002044
- UniProt
- P32455
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