MC4R 抗体
-
- 抗原 See all MC4R 抗体
- MC4R (Melanocortin 4 Receptor (MC4R))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This MC4R antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- MC4-R antibody detects endogenous levels of MC4-R protein.(region surrounding Glu315)
- 纯化方法
- Affinity chromatography
- Top Product
- Discover our top product MC4R Primary Antibody
-
anti-Melanocortin 4 Receptor (MC4R) (AA 1-50) antibody
MC4R 适用: 人, 小鼠, 大鼠 ELISA, IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 4 Receptor (MC4R) (N-Term) antibodyMC4R 适用: 人, 猴, 马 IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 4 Receptor (MC4R) (AA 6-20), (Extracellular), (N-Term) antibodyMC4R 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF, LCI 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 4 Receptor (MC4R) (AA 25-57) antibodyMC4R 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB52063 unconjugated
anti-Melanocortin 4 Receptor (MC4R) (Cytoplasmic Domain) antibodyMC4R 适用: 人, 猴, 绵羊, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 4 Receptor (MC4R) (C-Term) antibodyMC4R 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 4 Receptor (MC4R) (AA 21-33) antibodyMC4R 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 4 Receptor (MC4R) (Extracellular Domain) antibodyMC4R 适用: 人, 猴, 马, Chimpanzee, Gorilla, Orang-Utan IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 4 Receptor (MC4R) (C-Term) antibodyMC4R 适用: 人, 小鼠, 大鼠, 猴, 绵羊, 兔, Cow, 犬, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 4 Receptor (MC4R) (AA 1-50) antibody (Alexa Fluor 488)MC4R 适用: 人, 小鼠, 大鼠 IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 488
-
- 应用备注
-
ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- 抗原
- MC4R (Melanocortin 4 Receptor (MC4R))
- 别名
- MC4-R (MC4R 产品)
- 别名
- zMC4 antibody, si:dkey-151m6.62 antibody, mc4r antibody, MC4R antibody, LOC100218148 antibody, Mc4-r antibody, melanocortin 4 receptor antibody, mc4r antibody, MC4R antibody, Mc4r antibody
- 背景
- MC4 receptor is the fourth member of the five known melanocortin receptors (MCRs) belonging to the rhodopsin-like family of G protein-coupled receptors (GPCRs). These five MCRs form a unique family of GPCRs, marked by their unusually short coding sequence and the absence of highly conserved amino acid residues or motifs common to most GPCRs. All MCRs signal through the cyclic adenosine 3', 5'-monophosphate (cAMP) pathway. With the exception of MC2R, all MCRs are activated by both adrenocorticotropin (ACTH) and melanocyte-stimulating hormones (MSHs and mainly alpha-MSH). The MC4R receptor is expressed primarily in the brain, and unlike the other melanocortin receptors, MC4R is not expressed in adrenal cortex or in melanocytes. Genetic studies of mice and humans have established a critical role of MC4 Receptor in appetite regulation. Heterozygous mutations in MC4 Receptor account for 1-6 % of severe cases of human obesity.Synonyms: MC4R, Melanocortin receptor 4
- 分子量
- approx. 37 kDa
- 基因ID
- 4160
- NCBI登录号
- NP_005903
- UniProt
- P32245
- 途径
- Hormone Transport, cAMP Metabolic Process, Feeding Behaviour
-
