BAI1 抗体
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北京 101111
Quick Overview for BAI1 抗体 (ABIN317742)
抗原
See all BAI1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of BAI-1 protein.(region surrounding Gln732)
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纯化方法
- Affinity Chromatography using epitope-specific immunogen
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anti-Brain-Specific Angiogenesis Inhibitor 1 (BAI1) (Internal Region) antibody
BAI1 适用: 人, 小鼠, 大鼠 IHC, ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Brain-Specific Angiogenesis Inhibitor 1 (BAI1) antibodyBAI1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Brain-Specific Angiogenesis Inhibitor 1 (BAI1) (AA 1537-1567), (C-Term) antibodyBAI1 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB02096 unconjugated
anti-Brain-Specific Angiogenesis Inhibitor 1 (BAI1) (AA 97-112), (Extracellular) antibodyBAI1 适用: 小鼠 IHC, WB, IF, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Brain-Specific Angiogenesis Inhibitor 1 (BAI1) (AA 60-350) antibodyBAI1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Brain-Specific Angiogenesis Inhibitor 1 (BAI1) antibodyBAI1 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Brain-Specific Angiogenesis Inhibitor 1 (BAI1) (C-Term) antibodyBAI1 适用: 人, 小鼠, 大鼠, 猴, Cow, 小鸡, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Brain-Specific Angiogenesis Inhibitor 1 (BAI1) (AA 691-740) antibodyBAI1 适用: 人, 小鼠 IHC, ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Brain-Specific Angiogenesis Inhibitor 1 (BAI1) (AA 31-350) antibodyBAI1 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Brain-Specific Angiogenesis Inhibitor 1 (BAI1) (AA 97-112), (Extracellular) antibody (FITC)BAI1 适用: 小鼠 FACS, LCI 宿主: 兔 Polyclonal FITC
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应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))
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别名
- BAI1
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背景
- Brain-specific angiogenesis inhibitors, including BAI-1, BAI-2 and BAI-3, are integral membrane proteins belonging to the G protein-coupled receptor 2 family. In addition to inhibiting angiogenesis in the brain, BAI proteins are also expressed in the heart, thymus, skeletal muscle, and a variety of cell lines. BAI-1 protein is specifically expressed in the brain and found to localize to the cytoplasm and membrane in neuronal cells of the cerebral cortex. Reduced expression of BAI-1 in some glioblastoma cell lines and cancer tissues implicates the functional role of BAI-1 as an inhibitor of angiogenesis. The exact mechanisms underlying BAI-1 anti-angiogenetic activity are still being investigated. BAI-1 may be involved in mediating the p53 signal in suppression of glioblastoma, as well as in cell adhesion and signal transduction. Additional research shows an inverse correlation with vascularization and BAI-1 expression in both colorectal carcinomas and pulmonary adenocarcinomas.Synonyms: BAI-1, Brain-specific angiogenesis inhibitor 1
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分子量
- approx. 174 kDa
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基因ID
- 575
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NCBI登录号
- NP_001693
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UniProt
- O14514
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途径
- p53 Pathway
抗原
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