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Endothelin-1 Receptor 抗体

EDNRA 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317635
发货至: 中国
  • 抗原 See all Endothelin-1 Receptor (EDNRA) 抗体
    Endothelin-1 Receptor (EDNRA) (Endothelin Receptor Type A (EDNRA))
    适用
    • 38
    • 25
    • 20
    • 15
    • 15
    • 14
    • 13
    • 4
    • 4
    • 2
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    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 43
    • 3
    • 3
    • 1
    克隆类型
    • 48
    • 2
    多克隆
    标记
    • 30
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    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This Endothelin-1 Receptor antibody is un-conjugated
    应用范围
    • 36
    • 17
    • 14
    • 10
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    This antibody detects endogenous levels of Endothelin Receptor A (ETAR) protein.(region surrounding asn427)
    纯化方法
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product EDNRA Primary Antibody
  • 应用备注
    ELISA: 1/5000-1/10000. Western Blot: 1/500-1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Endothelin-1 Receptor (EDNRA) (Endothelin Receptor Type A (EDNRA))
    别名
    Endothelin A Receptor (EDNRA 产品)
    别名
    ET-A antibody, ETA antibody, ETA-R antibody, ETAR antibody, ETRA antibody, hET-AR antibody, ET-AR antibody, Endor antibody, Eta antibody, RGD1559432 antibody, ETa antibody, Gpcr10 antibody, ednr-a antibody, ednra antibody, wu:fb75g12 antibody, ednraa antibody, eta antibody, etar antibody, etra antibody, zgc:85942 antibody, endothelin receptor type A antibody, endothelin receptor type Aa antibody, endothelin receptor type A L homeolog antibody, endothelin receptor type Ab antibody, EDNRA antibody, Ednra antibody, ednraa antibody, ednra.L antibody, ednra antibody, ednrab antibody
    背景
    Endothelin receptor A (ETAR), also known as EDNRA, ET1 receptor, ETA, EDN1 and ET-AR, is a member of the guanine-binding regulatory protein-coupled receptor family. ETAR binds endothelins and has the highest affinity for its ligand, ET1, as compared to the ETBR receptor. Both ET receptors, ETAR and ETBR, are activated by ET1, which results in inhibition of active lens sodiumpotassium transport. Activation of the ET receptors also causes an increase in cytoplasmic calcium concentration in cultured lens epithelial cells. In addition, ETAR induces arachidonic acid accumulation. ETAR has seven hydrophobic transmembrane domains and is expressed in aorta, lung, atrium, kidney, placenta and prostate. Specifically, placental vascular smooth muscle cells (PVSMCs) exclusively express ETAR.Synonyms: EDNRA, ET-A, ETA, ETA-R, ETRA, Endothelin-1 receptor, endothelin receptor type A, hET-AR
    分子量
    approx. 50 kDa
    基因ID
    1909
    NCBI登录号
    NP_001159527
    UniProt
    P25101
    途径
    cAMP Metabolic Process
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