PHLDA1 抗体
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- 抗原 See all PHLDA1 抗体
- PHLDA1 (Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PHLDA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody detects endogenous levels of TDAG51 protein.(region surrounding Ala149)
- 纯化方法
- Affinity Chromatography using epitope-specific immunogen.
- Top Product
- Discover our top product PHLDA1 Primary Antibody
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anti-Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1) (AA 1-109) antibody
PHLDA1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A5 unconjugated
anti-Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1) (AA 1-138) antibodyPHLDA1 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1) (AA 1-259) antibodyPHLDA1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1) (N-Term) antibodyPHLDA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1) (AA 251-360) antibodyPHLDA1 适用: 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1) (C-Term) antibodyPHLDA1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1) (C-Term) antibodyPHLDA1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1) (AA 1-259) antibodyPHLDA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1) (AA 218-267) antibodyPHLDA1 适用: 人, 小鼠, Cow, 豚鼠, 马, 兔, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1) (AA 290-339) antibodyPHLDA1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 containing 0,05 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- PHLDA1 (Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1))
- 别名
- TDAG51 / PHLDA1 (PHLDA1 产品)
- 别名
- DT1P1B11 antibody, PHRIP antibody, TDAG51 antibody, Tdag antibody, pleckstrin homology like domain family A member 1 antibody, pleckstrin homology like domain, family A, member 1 antibody, pleckstrin homology-like domain, family A, member 1 antibody, pleckstrin homology-like domain, family A, member 1 L homeolog antibody, PHLDA1 antibody, Phlda1 antibody, phlda1.L antibody
- 背景
- Cytotoxic T lymphocyte (CTL)-mediated cytotoxicity constitutes an important component of specific effector mechanisms in immunosurveillance against virus-infected or -transformed cells. Two mechanisms appear to account for this activity, one of which is the perforin-based process. Independently, a FAS-based mechanism involves the transducing molecule FAS (APO-1) and its ligand (FAS-L). The human FAS (APO-1) protein is a 48 kDa cell surface glycoprotein that belongs to a family of receptors that includes CD40, nerve growth factor receptors and tumor necrosis factor receptors. The FAS antigen is expressed on a broad range of lymphoid cell lines, and is expressed at high levels in T cells subsequent to crosslinking of the T cell receptor (TCR). A previously undescribed protein, TDAG51, restores activation- induced apoptosis in cells that have lost the ability to display Fas in response to activation. Thus, TDAG51 plays a critical role in T cell apoptosis by coupling TCR.Synonyms: Apoptosis-associated nuclear protein, PHRIP, PQ-rich protein, PQR protein, Pleckstrin homology-like domain family A member 1, Proline- and glutamine-rich protein, Proline- and histidine-rich protein, T-cell death-associated gene 51 protein
- 基因ID
- 22822
- NCBI登录号
- NP_031376
- UniProt
- Q8WV24
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