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SRSF3 抗体

SRSF3 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN317610
发货至: 中国
  • 抗原 See all SRSF3 抗体
    SRSF3 (serine/arginine-Rich Splicing Factor 3 (SRSF3))
    适用
    • 36
    • 12
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 31
    • 5
    克隆类型
    • 30
    • 6
    多克隆
    标记
    • 26
    • 2
    • 2
    • 2
    • 2
    • 2
    This SRSF3 antibody is un-conjugated
    应用范围
    • 36
    • 23
    • 13
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of SFRS3 protein(region surrounding Phe151).
    交叉反应 (详细)
    Species reactivity (tested):Human and Mouse.
    纯化方法
    Affinity chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product SRSF3 Primary Antibody
  • 应用备注
    Western Blot: 1/500-1/1000. ELISA: 1/5000-1/10000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.2, 0.05 % Sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SRSF3 (serine/arginine-Rich Splicing Factor 3 (SRSF3))
    别名
    SFRS3 (SRSF3 产品)
    别名
    SFRS3 antibody, SRp20 antibody, AL024116 antibody, Sfrs3 antibody, X16 antibody, sfrs3 antibody, srp20 antibody, SRP20 antibody, si:zc263a23.9 antibody, zgc:86626 antibody, serine and arginine rich splicing factor 3 antibody, serine/arginine-rich splicing factor 3 antibody, serine/arginine-rich splicing factor 3 S homeolog antibody, serine/arginine-rich splicing factor 3a antibody, SRSF3 antibody, Srsf3 antibody, srsf3.S antibody, srsf3a antibody
    背景
    Pre-mRNA splicing enhancer elements are short RNA sequences capable of activating weak splice sites in nearby introns that are required for accurate splice site recognition and the control of alternative splicing. Splicing enhancer elements contain specific binding sites for serine/arginine (SR)-rich splicing factors, which include SC35, 9G8, SRp20, and SF2/ASF. The family of SR factors all contain one or more RNA recognition motifs (RRM) and an arginine/ serine(RS)-rich domain. They are not only essential for constitutive splicing but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. The majority of SR proteins, including SC35 and SRp40, are confined to the nucleus, while SF2/ASF, SRp20, and 9G8 are continuously shuttled between the nucleus and the cytoplasm and contribute to mRNA transport. The activity of SR proteins in regulated splicing is antagonized by members of the hnRNP A/B family of proteins, which induce drastic shifts in the selection of splicing sites. An additional SR-associated protein, p32, tightly associates with SR factors and preferentially inhibits ASF/SF2 functioning as both a splicing enhancer and splicing repressor protein by preventing the stable interaction of ASF/SF2 and RNA.Synonyms: Pre-mRNA-splicing factor SRP20, SRP20, Splicing factor arginine/serine-rich 3
    分子量
    approx. 25 kDa
    基因ID
    6428
    NCBI登录号
    NP_003008
    UniProt
    P84103
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