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TARDBP 抗体 (N-Term)

This anti-TARDBP antibody is a 小鼠 单克隆 antibody detecting TARDBP in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN317572
发货至: 中国

Quick Overview for TARDBP 抗体 (N-Term) (ABIN317572)

抗原

See all TARDBP 抗体
TARDBP (TAR DNA Binding Protein (TARDBP))

适用

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宿主

  • 91
  • 21
  • 1
小鼠

克隆类型

  • 77
  • 36
单克隆

标记

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  • 5
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This TARDBP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

克隆位点

K1B8
  • 抗原表位

    • 15
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    • 1
    • 1
    AA 1-260, N-Term

    特异性

    The antibody recognizes Human TARDBP. Other species not tested.

    产品特性

    Synonyms: TDP43, TDP-43, TAR DNA-binding protein 43

    纯化方法

    Protein-G Affinity Chromatography

    免疫原

    Recombinant Human TARDBP (1-260 aa) purified from E. coli.

    亚型

    IgG1
  • 应用备注

    ELISA. Western blot (1/1,000-1/2,000). Immunohistochemistry on Paraffin Sections (1/50-1/100).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.4, 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    TARDBP (TAR DNA Binding Protein (TARDBP))

    别名

    TARDBP

    背景

    TAR DNA binding protein (TARDBP), also known as TDP-43, is a cellular protein. TARDBP was identified as the disease accumulating protein in patients with frontotemporal lobar degeneration (FTLD) with ubiquitin inclusions (FTLD-U) and in amyotrophic lateral sclerosis (ALS). TARDBP functions as a DNA-binding protein and specifically binds to the TAR DNA sequence motifs of HIV. Via this association with TAR motifs, TARDBP acts as a transcriptional repressor and inhibits HIV-1 transcription. In addition, this protein regulates alternate splicing of the cystic fibrosis transmembrane receptor (CFTR) gene.Synonyms: TAR DNA-binding protein 43, TDP-43, TDP43

    基因ID

    23435

    UniProt

    Q13148

    途径

    Positive Regulation of Peptide Hormone Secretion
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