Tyrosine Hydroxylase 抗体
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- 抗原 See all Tyrosine Hydroxylase (TH) 抗体
- Tyrosine Hydroxylase (TH)
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适用
- 人, 大鼠, 小鼠, Protozoa
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宿主
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绵羊
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克隆类型
- 多克隆
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标记
- This Tyrosine Hydroxylase antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 交叉反应
- 人, 小鼠, 灵长类, 大鼠
- 纯化方法
- affinity purified
- 免疫原
- Native rat tyrosine hydroxylase purified from pheochromocytoma.
- 亚型
- IgG
- Top Product
- Discover our top product TH Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 储存条件
- -20 °C
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- 抗原
- Tyrosine Hydroxylase (TH)
- 别名
- Tyrosine Hydroxylase (TH 产品)
- 别名
- DYT14 antibody, DYT5b antibody, TYH antibody, The antibody, CG10118 antibody, DH65B antibody, DTH antibody, Dmel\\CG10118 antibody, Pale antibody, Ple antibody, TH antibody, Th antibody, VII antibody, dTH1 antibody, dTH65B antibody, pale/ple antibody, th antibody, dyt14 antibody, dyt5b antibody, tyh antibody, tyrosine hydroxylase antibody, pale antibody, tyrosine 3-monooxygenase antibody, tyrosine hydroxylase S homeolog antibody, TH antibody, Th antibody, ple antibody, th antibody, th.S antibody, LOC100008895 antibody
- 背景
- Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine, epinephrine and norepinephrine. Therefore the regulation of the TH enzyme represents the central means for controlling the synthesis of these important catecholamines. TH has a large molecular diversity, resulting from differential splicing of its mRNA, which is tissue specific and might result in long term changes in activity of the enzyme and the availability of neurotransmitter at various synapses. The presence of different DNA sequences at the TH locus confers susceptibility to various disorders of the brain including manic-depression and schizophrenia. Parkinson's disease is also considered a TH deficiency, as low dopamine levels are a consistent neurochemical abnormality.
- 途径
- Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
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