FBXW7 抗体
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- 抗原 See all FBXW7 抗体
- FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FBXW7 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 产品特性
- F-box and WD-40 domain protein 7, FBXW7, CDC4,Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.
- 纯化方法
- Ammonium Sulfate Precipitation
- 免疫原
- Synthetic peptide dervied from the human FBXW7 protein
- Top Product
- Discover our top product FBXW7 Primary Antibody
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- 应用备注
- Antibody can be used for Western blotting (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.
- 限制
- 仅限研究用
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- 缓冲液
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- 抗原
- FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
- 别名
- FBXW7 (FBXW7 产品)
- 别名
- cdc4 antibody, AGO antibody, CDC4 antibody, FBW6 antibody, FBW7 antibody, FBX30 antibody, FBXO30 antibody, FBXW6 antibody, SEL-10 antibody, SEL10 antibody, hAgo antibody, hCdc4 antibody, 1110001A17Rik antibody, Cdc4 antibody, Fbw7 antibody, Fbwd6 antibody, Fbx30 antibody, Fbxo30 antibody, Fbxw6 antibody, F-box and WD repeat domain containing 7 antibody, F-box and WD-40 domain protein 7 antibody, Fbxw7 antibody, FBXW7 antibody, fbxw7 antibody
- UniProt
- Q969H0
- 途径
- Notch Signaling, EGFR Signaling Pathway
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