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CYP26A1 抗体 (C-Term)

CYP26A1 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal F27 P6 A1 unconjugated
产品编号 ABIN307114
发货至: 中国
  • 抗原 See all CYP26A1 抗体
    CYP26A1 (Cytochrome P450, Family 26, Subfamily A, Polypeptide 1 (CYP26A1))
    抗原表位
    • 15
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 56
    • 21
    • 19
    • 4
    • 2
    • 2
    宿主
    • 56
    • 4
    • 1
    小鼠
    克隆类型
    • 50
    • 11
    单克隆
    标记
    • 30
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP26A1 antibody is un-conjugated
    应用范围
    • 43
    • 18
    • 13
    • 13
    • 8
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 1
    • 1
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    产品特性
    CYP450 26 (EC 1.14.-.-), Retinoic acid-metabolizing cytochrome, P450 retinoic acid-inactivating 1, P450RAI, hP450RAI, Retinoic acid 4-hydroxylase,The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP26A1, also referred to as retinoic acid-4-hydroxylase, is a major retinoic acid catabolic enzyme. CYP26A1 plays an important role in protecting tailbud tissues from inappropriate exposure to retinoic acid. CYP26A1 transcription is epigenetically regulated by nuclear retinoic acid receptors 2. Mutations in the gene encoding for CYP26A1 are associated with caudal agenesis and spina bifida, imperforate anus, agenesis of the caudal portions of the digestive and urogenital tracts, and malformed lumbosacral skeletal elements. CYP26A1 is upregulated in adenomatous polyposis coli mouse adenomas, human FAP adenomas, human sporadic colon carcinomas, and in the intestine of adenomatous polyposis coli(mcr) mutant zebrafish embryos.
    纯化方法
    Protein A/G Chromatography
    免疫原
    Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the C-terminus of the human CYP450 26A1 protein and mouse myeloma Ag8563 cells.
    克隆位点
    F27 P6 A1
    亚型
    IgG2b
    Top Product
    Discover our top product CYP26A1 Primary Antibody
  • 应用备注
    Antibody can be used for Western blotting (1-2 μg/mL) and immunohistochemistry on formalin-fixed, paraffin-embedded tissues (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.
    限制
    仅限研究用
  • 缓冲液
    Provided as solution in phosphate buffered saline with 0.08 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • 抗原
    CYP26A1 (Cytochrome P450, Family 26, Subfamily A, Polypeptide 1 (CYP26A1))
    别名
    Cytochrome p450 26A1 (CYP26A1 产品)
    别名
    CP26 antibody, CYP26 antibody, P450RAI antibody, P450RAI1 antibody, Cyp26 antibody, P450RA antibody, RAH antibody, RACE antibody, XCYP26A1 antibody, cyp26 antibody, xCYP26 antibody, cp26 antibody, p450rai antibody, p450rai1 antibody, CYP26A antibody, cb24 antibody, id:ibd5061 antibody, wu:fb81e05 antibody, cytochrome P450 family 26 subfamily A member 1 antibody, cytochrome P450, family 26, subfamily a, polypeptide 1 antibody, cytochrome P450 family 26 subfamily A member 1 S homeolog antibody, cytochrome P450 family 26 subfamily A member 1 L homeolog antibody, cytochrome P450, family 26, subfamily A, polypeptide 1 antibody, CYP26A1 antibody, Cyp26a1 antibody, cyp26a1.S antibody, cyp26a1.L antibody, cyp26a1 antibody
    途径
    Retinoic Acid Receptor Signaling Pathway, Monocarboxylic Acid Catabolic Process
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