CYP2A6 抗体 (C-Term)
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- 抗原 See all CYP2A6 抗体
- CYP2A6 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CYP2A6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人
- 产品特性
- CYP2A6, CYP450 2A6 (EC 1.14.14.1), CYPIIA6, Coumarin 7-hydroxylase,The cytochrome P450 proteins (CYPs) are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. P450 enzymes are classified into subfamilies based on their sequence similarities. CYP2A6 is a liver enzyme that metabolizes a number of drugs and a variety of procarcinogens, though it is primarily responsible for the metabolism of nicotine, the major addictive agent in tobacco. CYP2A6 inactivates nicotine to cotinine, and then cotinine to 3-hydroxycotinine. Differences in CYP2A6 genotypes are related to nicotine dependence, and may influence smoking habits and withdrawal symptoms in individuals that are quitting smoking. This suggests that an individualized smoking cessation program may be designed based on CYP2A6 genotypes.
- 纯化方法
- Protein A/G Chromatography
- 免疫原
- Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with Synthetic peptide conjugated to ovalbumin derived from the C-terminus of CYP2A6 and mouse myeloma Ag8563 cells. Antigen identical in CYP2A6, 2A7 and 2A13.
- 克隆位点
- F16 P2 D8
- 亚型
- IgG1
- Top Product
- Discover our top product CYP2A6 Primary Antibody
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anti-Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6) antibody
CYP2A6 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1D2 unconjugated
anti-Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6) antibodyCYP2A6 适用: 人 WB, IF, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 2A8 unconjugated
anti-Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6) antibodyCYP2A6 适用: 人 WB, IF, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 3C1 unconjugated
anti-Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6) (AA 1-494) antibodyCYP2A6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6) (AA 1-494) antibodyCYP2A6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6) (AA 395-494) antibodyCYP2A6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B11 unconjugated
anti-Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6) (N-Term) antibodyCYP2A6 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6) (N-Term) antibodyCYP2A6 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6) (N-Term) antibodyCYP2A6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6) (AA 86-267) antibodyCYP2A6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Antibody can be used for Western blotting (1-2 μg/mL), immunofluorescence and immunohistochemistry (formalin-fixed, paraffin-embedded tissues). ELISA titer to be determined by end-user. Optimal concentration should be evaluated by serial dilutions.
- 限制
- 仅限研究用
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- 缓冲液
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- 抗原
- CYP2A6 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))
- 别名
- Cytochrome P450 2A6 (CYP2A6 产品)
- 别名
- CPA6 antibody, CYP2A antibody, CYP2A3 antibody, CYPIIA6 antibody, P450C2A antibody, P450PB antibody, cyp2a6 antibody, cytochrome P450 family 2 subfamily A member 6 antibody, cytochrome P450 2A6 antibody, cytochrome P450 family 2 subfamily A member 6 L homeolog antibody, CYP2A6 antibody, cyp2a6.L antibody
- UniProt
- P05177
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