LKB1 抗体
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- 抗原 See all LKB1 (STK11) 抗体
- LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LKB1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 人
- 产品特性
- Serine/threonine-protein kinase 11, Serine/threonine-protein kinase LKB1,Germline mutations of the LKB1 (STK11) tumor suppressor gene can lead to Peutz-Jeghers syndrome (PJS) and a marked predisposition to cancer. LKB1 encodes a serine/threonine kinase that is inactivated in PJS. The tumor suppressor protein PTEN is a LKB1-interacting protein. Several point mutations in LKB1 are associated with PJS and may disrupt the interaction with PTEN suggesting that the loss of this interaction might contribute to PJS. PTEN and LKB1 are predominantly cytoplasmic and nuclear, respectively, the interaction of the two leads to a cytoplasmic relocalization of LKB1. PTEN is a substrate of the kinase LKB1 in vitro.
- 纯化方法
- Ammonium Sulfate Precipitation
- 免疫原
- Synthetic peptide derived from the human LKB1/STK11 serine/threonine kinase protein.
- 亚型
- IgG
- Top Product
- Discover our top product STK11 Primary Antibody
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anti-serine/threonine Kinase 11 (STK11) (AA 134-433) antibody
STK11 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 11 (STK11) antibodySTK11 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 11 (STK11) (AA 14-44), (N-Term) antibodySTK11 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB3547 unconjugated
anti-serine/threonine Kinase 11 (STK11) (AA 14-44) antibodySTK11 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 11 (STK11) (pSer428) antibodySTK11 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 11 (STK11) (AA 19-48) antibodySTK11 适用: 人 WB, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 11 (STK11) (Tyr1313) antibodySTK11 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 11 (STK11) (AA 1-433) antibodySTK11 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 11 (STK11) (Internal Region) antibodySTK11 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 11 (STK11) (pThr189) antibodySTK11 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Antibody can be used for Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.
- 限制
- 仅限研究用
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- 缓冲液
- Purified IgG in phosphate buffered saline and 0.08 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- 抗原
- LKB1 (STK11) (serine/threonine Kinase 11 (STK11))
- 别名
- LKB1/STK11 Serine/Threonine Kinase (STK11 产品)
- 别名
- pjs antibody, LKB1 antibody, XEEK1 antibody, Stk11 antibody, PJS antibody, hLKB1 antibody, AA408040 antibody, Lkb1 antibody, Par-4 antibody, R75140 antibody, mLKB1 antibody, wu:fj61a05 antibody, zgc:110180 antibody, xeek1 antibody, serine/threonine kinase 11 antibody, polarization-related protein LKB1 antibody, serine/threonine kinase 11 L homeolog antibody, STK11 antibody, stk11 antibody, LOC662493 antibody, Stk11 antibody, stk11.L antibody
- UniProt
- Q15831
- 途径
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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