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SLA 抗体

SLA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN306901
发货至: 中国
  • 抗原 See all SLA 抗体
    SLA (Src-Like-Adaptor (SLA))
    适用
    • 16
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 12
    • 4
    克隆类型
    • 14
    • 2
    多克隆
    标记
    • 12
    • 2
    • 1
    • 1
    This SLA antibody is un-conjugated
    应用范围
    • 12
    • 9
    • 5
    • 3
    • 2
    • 2
    Western Blotting (WB)
    交叉反应
    产品特性
    Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins. Interacts with EPHA2, VAV1, LCP2 and PDGFRB. The C-terminal domain is essential for the homodimerization and the interaction with CBL. While the interaction with CBL is apparently mediated via the hydrophobic region of this domain, the highly charged region is apparently required for the homodimerization. Expressed in lung and fetal brain. Weakly expressed in heart, adult brain, placenta, liver, skeletal muscle, kidney and pancreas.
    纯化方法
    Ammonium Sulfate Precipitation
    免疫原
    Synthetic peptide derived from the human SLAP1 protein.
    亚型
    IgG
    Top Product
    Discover our top product SLA Primary Antibody
  • 应用备注
    Antibody can be used for Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.
    限制
    仅限研究用
  • 缓冲液
    Provided as solution in phosphate buffered saline with 0.08 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • 抗原
    SLA (Src-Like-Adaptor (SLA))
    别名
    SLAP1 (Src-like Adaptor Protein-1) (SLA 产品)
    别名
    SLA1 antibody, SLAP antibody, src-like-adapter antibody, SLA antibody, Slap1 antibody, Slap antibody, Slap-1 antibody, Src like adaptor antibody, Src-like-adaptor antibody, src-like adaptor antibody, SLA antibody, Sla antibody
    UniProt
    Q13239
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