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- 抗原 See all CACNA1C 抗体
- CACNA1C (Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CACNA1C antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 产品特性
- Neuronal voltage-gated calcium channel gamma-3 subunit, Transmembrane AMPAR regulatory protein gamma-3, Voltage-dependent calcium channel gamma-3 subunit,Voltage-dependent calcium channels (VDCCs) are large (>400 kDa) heteromers which contain, minimally, three core subunits 1, 2/ , in a 1:1:1 stoichiometry1. Expression of VDCC gene products in Xenopus oocytes, or transfected cells shows that the 1 subunits contain the ion channel pore while the auxiliary 2/ and subunits confer optimal cell surface expression and channel kinetics1. Until recently, the only exception to the above paradigm was the skeletal muscle VDCC, which, in addition to the 1, 2/ , core motif, also has an additional tightly associated integral membrane glycoprotein subunit termed 1. Upon co-expression with the 1.1, 2/ 1, 1a subunits of the skeletal muscle VDCC, subunits alter the peak currents, and the kinetics of channel activation and inactivation with the overall effect being a normalisation of currents to those resembling the endogenous channel2. Together, these results suggest that subunits modulate skeletal muscle VDCCs by stabilising their conformation. The 3 subunit is specifically localized in the brain, with the 2 and 4 subunits. It shares >60 % sequence homology with the 2 and 4 subunits and ~25 % sequence homology with the 1 and 5 subunits.
- 纯化方法
- Ammonium Sulfate Precipitation
- 免疫原
- Synthetic peptide derived from the rat calcium channel gamma3 subunit conjugated to KLH
- 亚型
- IgG
- Top Product
- Discover our top product CACNA1C Primary Antibody
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anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) (AA 1507-1733) antibody
CACNA1C 适用: 兔 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S57 unconjugated
anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) (AA 1507-1733) antibody (HRP)CACNA1C 适用: 兔 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S57 HRP
anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) (AA 1507-1733) antibody (FITC)CACNA1C 适用: 兔 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S57 FITC
anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) (AA 1507-1733) antibody (Biotin)CACNA1C 适用: 兔 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S57 Biotin
anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) (AA 1507-1733) antibody (PE)CACNA1C 适用: 兔 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S57 PE
anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) (AA 1507-1733) antibody (APC)CACNA1C 适用: 兔 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S57 APC
anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) (AA 1507-1733) antibody (PerCP)CACNA1C 适用: 兔 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S57 PerCP
anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) (AA 1507-1733) antibody (Atto 488)CACNA1C 适用: 兔 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S57 Atto 488
anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) (AA 1507-1733) antibody (Atto 594)CACNA1C 适用: 兔 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S57 Atto 594
anti-Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) (AA 1507-1733) antibody (Atto 390)CACNA1C 适用: 兔 WB, IHC, IP, IF, ICC, AA 宿主: 小鼠 Monoclonal S57 Atto 390
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- 应用备注
- This antibody can be used for Western blotting at 5-10 μg/mL. Optimal concentration should be evaluated by serial dilutions.
- 限制
- 仅限研究用
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- 缓冲液
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- 抗原
- CACNA1C (Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C))
- 别名
- Calcium Channel (CACNA1C 产品)
- 别名
- CACH2 antibody, CACN2 antibody, CACNL1A1 antibody, CCHL1A1 antibody, CaV1.2 antibody, LQT8 antibody, TS antibody, Cav1.2 antibody, Cchl1a1 antibody, MBC antibody, MELC-CC antibody, RATIVS302 antibody, isl antibody, C-LTCC antibody, CHCACHA1C antibody, ICA antibody, cav1.2 antibody, ca(v)1.2 antibody, CAV1.2 antibody, BCR antibody, rbc antibody, calcium voltage-gated channel subunit alpha1 C antibody, calcium channel, voltage-dependent, L type, alpha 1C subunit antibody, voltage-dependent L-type calcium channel subunit alpha-1C antibody, calcium channel, voltage-dependent, L type, alpha 1C subunit S homeolog antibody, Red blood cell count antibody, RNA, 7SL, cytoplasmic 263, pseudogene antibody, CACNA1C antibody, Cacna1c antibody, cacna1c antibody, LOC100442085 antibody, cacna1c.S antibody, RBC antibody, RN7SL263P antibody
- UniProt
- O60359
- 途径
- Hormone Transport, Carbohydrate Homeostasis
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