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PTGER3 抗体

PTGER3 适用: 人 WB 宿主: 小鼠 Monoclonal 5F5 unconjugated
产品编号 ABIN306865
发货至: 中国
  • 抗原 See all PTGER3 抗体
    PTGER3 (Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3))
    适用
    • 54
    • 21
    • 9
    • 7
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    宿主
    • 64
    • 5
    • 1
    小鼠
    克隆类型
    • 67
    • 3
    单克隆
    标记
    • 39
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    This PTGER3 antibody is un-conjugated
    应用范围
    • 41
    • 29
    • 19
    • 17
    • 15
    • 11
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    Cow, 人, 大鼠
    产品特性
    Prostaglandin E2 Receptor Subtype EP3,Prostaglandins (PG's) are produced by the metabolism of arachidonic acid. PGE-2 is one of the five physiologically significant prostanoids known. Its wide spectrum of physiologic and pharmacologic effects in various tissues are mediated through binding to the PGE-2 receptors (EP1, EP2, EP3 & EP4). These include effects on the immune, endocrine, cardiovascular, renal and reproductive systems as well as smooth muscle. It is also one of the most abundant of the prostanoid family in the brain where it plays an important role in many neural functions, particularly in newborn babies, and as a mediator of inflammation. PGE-2 signals through a family of G-protein coupled receptors known as EP receptors. There are 4 subtypes of EP receptors, known as EP1, EP2, EP3 and EP4. EP3 receptors are 365-425 amino acid proteins. There are currently 4 known isoforms of EP3 receptors named EP3A, 3B, 3C and 3D. Each of has different physiological function, but differ only in the carboxyl terminus and how they couple to their respective G-proteins. EP3 receptors are involved in water absorption, gastric acid secretion, uterine contraction, neurotransmitter release and the hydrolysis of fat cells (lipolysis). EP3 receptors also act as a mediator of neural inflammation. These receptors are mainly localized in the brain, kidney, stomach, uterus and ovaries.
    纯化方法
    Protein A/G Chromatography
    免疫原
    Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant human EP3 receptor protein and mouse myeloma cells.
    克隆位点
    5F5
    亚型
    IgG2a
    Top Product
    Discover our top product PTGER3 Primary Antibody
  • 应用备注
    This antibody can be used for Western blot analysis (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.
    限制
    仅限研究用
  • 缓冲液
    Provided as solution in phosphate buffered saline with 0.08 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • 抗原
    PTGER3 (Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3))
    别名
    Prostaglandin-E2 receptor EP3 (PTGER3 产品)
    别名
    PTGER3 antibody, EP3 antibody, EP3-I antibody, EP3-II antibody, EP3-III antibody, EP3-IV antibody, EP3e antibody, PGE2-R antibody, PTGEREP3 antibody, Rep3 antibody, rEP3a antibody, rEP3b antibody, Pgerep3 antibody, Ptgerep3 antibody, prostaglandin E receptor 3 antibody, prostaglandin E receptor 3 L homeolog antibody, prostaglandin E receptor 3 (subtype EP3) antibody, PTGER3 antibody, ptger3.L antibody, Ptger3 antibody
    UniProt
    P34980
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