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PTGER2 抗体

PTGER2 适用: 人 WB 宿主: 小鼠 Monoclonal 3E6 unconjugated
产品编号 ABIN306864
发货至: 中国
  • 抗原 See all PTGER2 抗体
    PTGER2 (Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2))
    适用
    • 64
    • 30
    • 16
    • 13
    • 7
    • 5
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    • 3
    • 3
    • 3
    • 1
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    • 1
    宿主
    • 59
    • 7
    小鼠
    克隆类型
    • 59
    • 7
    单克隆
    标记
    • 44
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This PTGER2 antibody is un-conjugated
    应用范围
    • 51
    • 32
    • 16
    • 15
    • 14
    • 13
    • 13
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
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    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    Cow, 人, 大鼠
    产品特性
    Prostaglandin E2 Receptor Subtype EP2, Provided under license from Allergan, Inc. United States Patent No. 5,716,835,Prostaglandins (PG's) are produced by the metabolism of arachidonic acid. PGE-2 is one of the five physiologically significant prostanoids known. Its wide spectrum of physiologic and pharmacologic effects in various tissues are mediated through binding to the PGE-2 receptors (EP1, EP2, EP3 & EP4). These include effects on the immune, endocrine, cardiovascular, renal and reproductive systems as well as smooth muscle. It is also one of the most abundant of the prostanoid family in the brain where it plays an important role in many neural functions, particularly in newborn babies, and as a mediator of inflammation. PGE-2 signals through a family of G-protein coupled receptors known as EP receptors. There are 4 subtypes of EP receptors, known as EP1, EP2, EP3 and EP4. EP2 receptors are 358 amino acid proteins with a short third intracellular loop. EP2 receptors stimulate adenylyl cyclase by their coupling to Gs and do not undergo PGE-2-induced internalization. The EP2 receptors is involved with the contration and relaxation of smooth muscle tissue. These receptors are mainly localized in lung and placental tissues and in smooth muscle.
    纯化方法
    Protein A/G Chromatography
    免疫原
    Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant human EP2 receptor protein and mouse myeloma cells.
    克隆位点
    3E6
    亚型
    IgG1
    Top Product
    Discover our top product PTGER2 Primary Antibody
  • 应用备注
    This antibody can be used for Western blot analysis (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.
    限制
    仅限研究用
  • 缓冲液
    Provided as solution in phosphate buffered saline with 0.08 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • 抗原
    PTGER2 (Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2))
    别名
    Prostaglandin-E2 receptor EP2 (PTGER2 产品)
    别名
    EP2 antibody, Ptgerep2 antibody, ptger2 antibody, ptger2l antibody, zgc:63974 antibody, MGC69060 antibody, PTGER2 antibody, Ptger-ep2 antibody, si:ch211-13n20.1 antibody, si:dkey-29m11.3 antibody, zgc:136608 antibody, prostaglandin E receptor 2 antibody, prostaglandin E receptor 2 (subtype EP2) antibody, prostaglandin E receptor 2a (subtype EP2) antibody, prostaglandin E receptor 2 S homeolog antibody, prostaglandin E receptor 2b (subtype EP2) antibody, PTGER2 antibody, Ptger2 antibody, ptger2a antibody, ptger2.S antibody, ptger2b antibody
    UniProt
    Q62928
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