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- 抗原 See all RIT2 抗体
- RIT2 (Ras-Like Without CAAX 2 (RIT2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This RIT2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人, 小鼠
- 产品特性
- Rit and its neuron-specific homologue, Rin, define a recently discovered subfamily of Ras-related GTPases. Rit and Rin are membrane-associated in spite of the fact that they lack a CAAX box or similar C-terminal lipidation motif. Rit and Rin display 64 % amino acid sequence identity and share a unique nine amino acid effector domain (DPTIEDAYK) that is 100 % conserved between the murine and human proteins. Although the effector domain sequences of Rit and Rin are very similar to that of Ras, Rit and Rin have been shown to interact with the known Ras-binding proteins RalGDS, Rlf and AF-6, but not the Raf kinases, RIN1 or the p110 subunit of PI3 kinase. For this reason, it has been suggested that Rit and Rin may play important roles in the regulation of signaling pathways distinct from those controlled by Ras.
- 免疫原
- Hybridoma produced by the fusion of splenocytes from mice immunized with full-length recombinant human Rin protein and mouse myeloma cells.
- 克隆位点
- 27G2
- 亚型
- IgG2b
- Top Product
- Discover our top product RIT2 Primary Antibody
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anti-Ras-Like Without CAAX 2 (RIT2) (AA 1-150) antibody
RIT2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ras-Like Without CAAX 2 (RIT2) (AA 1-217) antibodyRIT2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F2 unconjugated
anti-Ras-Like Without CAAX 2 (RIT2) antibodyRIT2 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 4A6 unconjugated
anti-Ras-Like Without CAAX 2 (RIT2) antibodyRIT2 适用: 人, 大鼠, 猴, 犬 WB, IHC, FACS 宿主: 小鼠 Monoclonal 3F4 unconjugated
anti-Ras-Like Without CAAX 2 (RIT2) (AA 1-217) antibodyRIT2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ras-Like Without CAAX 2 (RIT2) antibodyRIT2 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 27G2 unconjugated
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- 应用备注
- Antibody detects recombinant Rin protein expressed in 293 cells by Western blot analysis at a concentration of 0.5 to 1 μg/mL. Does not cross-react with Rit protein. Optimal concentration should be evaluated by serial dilutions.
- 限制
- 仅限研究用
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- 缓冲液
- Provided as sterile filtered solution containing 20 mM sodium phosphate, 150 mM sodium chloride, 50 % glycerol at pH 7.5 and 3 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- 抗原
- RIT2 (Ras-Like Without CAAX 2 (RIT2))
- 别名
- Rin (RIT2 产品)
- 别名
- RIBA antibody, RIN antibody, ROC2 antibody, Rin antibody, Rit1 antibody, Roc2 antibody, RIT2 antibody, Ras like without CAAX 2 antibody, Ras-like without CAAX 2 antibody, RIT2 antibody, Rit2 antibody
- UniProt
- Q13671
- 途径
- Neurotrophin Signaling Pathway
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