The immunogen used for the anti-mouse pic region was a GST fusion proteincorresponding to the amino acid 612-691 of the C terminus region and having amolecular weight of 90 kD. Familial juvenile nephronophthisis (NPH) is anautosomal recessive cystic kidney disease that is the primary inherited cause ofchronic renal failure in children. Synonyms: mpic, rabbit anti mouse nephrophthisis, pic.