Bcl-2 抗体
Quick Overview for Bcl-2 抗体 (ABIN306549)
抗原
See all Bcl-2 (BCL2) 抗体适用
宿主
克隆类型
标记
应用范围
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亚型
- IgG
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限制
- 仅限研究用
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- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
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别名
- bcl-2
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背景
- Human hematopoetic malignancies are often characterized by gene rearrangements that deregulate gene expression. Antibodies to human bcl-2 (B cell leukemia/lymphoma 2) are directed against the gene isolated at the chromosomal breakpoint t(14,18) Bcl-2 which suppress programmed cell death (apoptosis) and appears to be modulated by association with bax, a cell death promoter. Synonyms: hbcl2, sheep anti human bcl 2, bcl-2.
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UniProt
- P10415
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途径
- MAPK Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
抗原
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