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IL-33 抗体

IL33 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4-00E-09 unconjugated
产品编号 ABIN361077
发货至: 中国
  • 抗原 See all IL-33 (IL33) 抗体
    IL-33 (IL33) (Interleukin 33 (IL33))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This IL-33 antibody is un-conjugated
    应用范围
    • 84
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    Western Blotting (WB), ELISA
    纯化方法
    The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
    免疫原
    Recombinant human IL-33 (112-270aa), Accession / GI number: NP_254274
    克隆位点
    4-00E-09
    亚型
    IgG2b kappa
    Top Product
    Discover our top product IL33 Primary Antibody
  • 应用备注
    Recommended dilution 1:500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1mg/ml
    缓冲液
    In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    IL-33 (IL33) (Interleukin 33 (IL33))
    别名
    IL33 (IL33 产品)
    别名
    IL33 antibody, C9orf26 antibody, DVS27 antibody, IL1F11 antibody, NF-HEV antibody, NFEHEV antibody, RP11-575C20.2 antibody, 9230117N10Rik antibody, Il-33 antibody, Il1f11 antibody, RGD1311155 antibody, interleukin 33 antibody, IL33 antibody, Il33 antibody
    背景
    Interleukin 33 (IL-33) is a 32kDa proinflammatory cytokine and intracellular nuclear factor with transcriptional regulatory properties. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1 (IL1 receptor-like-1), which is known also as ST2. Binding of IL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces expression of IL-4, IL-5, IL-13 and leads to severe pathological changes in mucosal organs and in vitro, it can be divided to N-terminal fragment of 12kDa and C-terminal fragment of 18kDa by cleavage of caspase-1.Concentration: 1 mg/ml
    途径
    Production of Molecular Mediator of Immune Response
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