ZBTB7A 抗体 (N-Term)
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- 抗原 See all ZBTB7A 抗体
- ZBTB7A (Zinc Finger and BTB Domain Containing 7A (ZBTB7A))
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抗原表位
- AA 125-163, N-Term
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZBTB7A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Zinc finger and BTB domain-containing protein 7A(ZBTB7A) detection. Tested with WB, IHC-P in Mouse,Rat.
- 序列
- DLLERQILAA DDVGDASQPD GAGPTDQRNL LRAKEYLEF
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Zinc finger and BTB domain-containing protein 7A(ZBTB7A) detection. Tested with WB, IHC-P in Mouse,Rat.
Gene Name: zinc finger and BTB domain containing 7A
Protein Name: Zinc finger and BTB domain-containing protein 7A - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of mouse ZBTB7A (125-163aa DLLERQILAADDVGDASQPDGAGPTDQRNLLRAKEYLEF), different from the related human sequence by eleven amino acids, and from the related rat sequence by one amino acid.
- 亚型
- IgG
- Top Product
- Discover our top product ZBTB7A Primary Antibody
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anti-Zinc Finger and BTB Domain Containing 7A (ZBTB7A) (AA 151-250) antibody
ZBTB7A 适用: 人 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 7A (ZBTB7A) antibodyZBTB7A 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 7A (ZBTB7A) (N-Term) antibodyZBTB7A 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 7A (ZBTB7A) (N-Term) antibodyZBTB7A 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 7A (ZBTB7A) (AA 1-108) antibodyZBTB7A 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 2A2 unconjugated
anti-Zinc Finger and BTB Domain Containing 7A (ZBTB7A) (C-Term) antibodyZBTB7A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 7A (ZBTB7A) antibodyZBTB7A 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 7A (ZBTB7A) (AA 114-163) antibodyZBTB7A 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 7A (ZBTB7A) (AA 224-273) antibodyZBTB7A 适用: 人, 小鼠, 大鼠, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 7A (ZBTB7A) (AA 108-157) antibodyZBTB7A 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, Pig, 猴, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- ZBTB7A (Zinc Finger and BTB Domain Containing 7A (ZBTB7A))
- 别名
- ZBTB7A (ZBTB7A 产品)
- 别名
- ZBTB7A antibody, FBI-1 antibody, FBI1 antibody, LRF antibody, ZBTB7 antibody, ZNF857A antibody, pokemon antibody, 9030619K07Rik antibody, 9130006G12Rik antibody, AI452336 antibody, Lrf antibody, Pokemon antibody, Zbtb7 antibody, OCZF antibody, zinc finger and BTB domain containing 7A antibody, zinc finger and BTB domain containing 7C antibody, zinc finger and BTB domain containing 7a antibody, ZBTB7A antibody, ZBTB7C antibody, Zbtb7a antibody
- 背景
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Zinc finger and BTB domain-containing protein 7A is a protein that in humans is encoded by the ZBTB7A gene. ZBTB7A has a critical oncosuppressive role in the prostate. Prostate-specific inactivation of ZBTB7A leads to a marked acceleration of PTEN loss-driven prostate tumorigenesis through bypass of PTEN loss-induced cellular senescence. It has been showed that ZBTB7A physically interacts with SOX9 and functionally antagonizes its transcriptional activity on key target genes such as MIA, which is involved in tumor cell invasion, and H19, a long noncoding RNA precursor for an RB-targeting microRNA. Inactivation of ZBTB7A in vivo leads to RB downregulation, bypass of PTEN loss-induced cellular senescence, and invasive prostate cancer. Notably, it has been also found that ZBTB7A is genetically lost, as well as downregulated at both the mRNA and protein levels, in a subset of human advanced prostate cancers. Therefore, ZBTB7A is identified as a context-dependent cancer gene that can act as an oncogene in some contexts but that also has oncosuppressive-like activity in PTEN-null tumors.
Synonyms: DKFZp547O146 antibody|Factor binding IST protein 1 antibody|Factor that binds to inducer of short transcripts protein 1 antibody|FBI-1 antibody|FBI1 antibody|HIV-1 1st-binding protein 1 antibody|HIV-1 inducer of short transcripts binding protein antibody|HIV-1 inducer of short transcripts-binding factor 1 antibody|Leukemia/lymphoma-related factor antibody|LRF antibody|lymphoma related factor antibody|MGC99631 antibody|POK erythroid myeloid ontogenic factor antibody|Pokemon antibody|POZ and Krueppel erythroid myeloid ontogenic factor antibody|TIP21 antibody|TTF-I-interacting peptide 21 antibody|ZBT7A_HUMAN antibody|ZBTB7 antibody|ZBTB7A antibody| Zinc finger and BTB domain containing 7A antibody|zinc finger and BTB domain containing 7A, HIV-1 inducer of short transcripts binding protein antibody|Zinc finger and BTB domain-containing protein 7A antibody|Zinc finger protein 857A antibody|Zinc finger- and BTB domain-containing protein 7 antibody|ZNF857A antibody - 基因ID
- 16969
- UniProt
- O88939
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