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- 抗原 See all FcRn 抗体
- FcRn (IgG receptor FcRn (FcRn))
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抗原表位
- AA 56-291
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FcRn antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for IgG receptor FcRn large subunit p51(FCGRT) detection. Tested with WB, IHC-P in Human.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for IgG receptor FcRn large subunit p51(FCGRT) detection. Tested with WB, IHC-P in Human.
Gene Name: Fc fragment of IgG receptor and transporter
Protein Name: IgG receptor FcRn large subunit p51 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E. coli-derived human FCGRT recombinant protein (Position: Q56-E291). Human FCGRT shares 70.2% and 68.9% amino acid (aa) sequence identity with mouse and rat FCGRT, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product FcRn Primary Antibody
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anti-IgG receptor FcRn (FcRn) antibody
FcRn 适用: 人 ELISA, IF, FACS, cELISA, Func 宿主: 小鼠 Monoclonal ADM31 unconjugated
anti-IgG receptor FcRn (FcRn) (AA 24-297) antibodyFcRn 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-IgG receptor FcRn (FcRn) (AA 24-365) antibodyFcRn 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-IgG receptor FcRn (FcRn) (AA 24-215) antibodyFcRn 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal FCGRT-2932 unconjugated
anti-IgG receptor FcRn (FcRn) (AA 24-297) antibodyFcRn 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 2B3B11 unconjugated
anti-IgG receptor FcRn (FcRn) (AA 24-297) antibodyFcRn 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 5F3D1 unconjugated
anti-IgG receptor FcRn (FcRn) (AA 25-300) antibodyFcRn 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-IgG receptor FcRn (FcRn) (N-Term) antibodyFcRn 适用: 人, 小鼠, 绵羊, Cow, 犬, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-IgG receptor FcRn (FcRn) antibodyFcRn 适用: 人, 小鼠 ELISA, IF, FACS, cELISA 宿主: 小鼠 Monoclonal DVN24 unconjugated
anti-IgG receptor FcRn (FcRn) (N-Term) antibodyFcRn 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- FcRn (IgG receptor FcRn (FcRn))
- 别名
- FCGRT (FcRn 产品)
- 别名
- FCRN antibody, alpha-chain antibody, FcRn antibody, Fc fragment of IgG receptor and transporter antibody, Fc receptor, IgG, alpha chain transporter antibody, FCGRT antibody, Fcgrt antibody
- 背景
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IgG receptor FcRn large subunit p51 is a protein that in humans is encoded by the FCGRT gene. This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. In addition, it is postulated that long-range cis inactivation of the FCGRT gene is responsible for hypercatabolism of IgG in myotonic dystrophy. The FCGRT gene is closely situated to the DMPK gene, which is mutant in DM.
Synonyms: Alpha chain antibody|Fc fragment of IgG, receptor transporter, alpha antibody|FCGRN_HUMAN antibody|FCGRT antibody|FcRn alpha chain antibody|FcRn antibody|FCRN, alpha chain antibody|IgG Fc fragment receptor transporter alpha chain antibody|IgG Gc receptor antibody| IgG receptor FcRn large subunit p51 antibody|IgG receptor FcRn large subunit p51 precursor antibody|Immunoglobulin receptor, intestinal, heavy chain antibody|Neonatal Fc receptor antibody - 基因ID
- 2217
- UniProt
- P55899
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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