ATP2A1/SERCA1 抗体 (Middle Region)
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- 抗原 See all ATP2A1/SERCA1 (ATP2A1) 抗体
- ATP2A1/SERCA1 (ATP2A1) (ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1))
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抗原表位
- AA 665-680, Middle Region
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ATP2A1/SERCA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Sarcoplasmic/endoplasmic reticulum calcium ATPase 1(ATP2A1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- EQREACRRAC CFARVE
- 交叉反应 （详细）
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Sarcoplasmic/endoplasmic reticulum calcium ATPase 1(ATP2A1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
Protein Name: Sarcoplasmic/endoplasmic reticulum calcium ATPase 1(SERCA1/SR Ca(2+)-ATPase 1) - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human SERCA1 ATPase(665-680aa EQREACRRACCFARVE), identical to the related rat and mouse sequences.
- 亚型
- IgG
- Top Product
- Discover our top product ATP2A1 Primary Antibody
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anti-ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1) (AA 522-612) antibody
ATP2A1 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1B11 unconjugated
anti-ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1) (AA 487-631) antibodyATP2A1 适用: 人, 小鼠, 猴 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 4F11F6 unconjugated
anti-ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1) (N-Term) antibodyATP2A1 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1) (AA 522-613) antibodyATP2A1 适用: 人 WB, ELISA, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 1B11 unconjugated
anti-ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1) antibodyATP2A1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1) (AA 974-1001), (C-Term) antibodyATP2A1 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB25882 unconjugated
anti-ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1) (AA 384-579) antibodyATP2A1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1) antibodyATP2A1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1) (AA 522-612) antibodyATP2A1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4B8 unconjugated
anti-ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1) (Internal Region) antibodyATP2A1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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- 抗原
- ATP2A1/SERCA1 (ATP2A1) (ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1))
- 别名
- ATP2A1 (ATP2A1 产品)
- 别名
- cb279 antibody, serca antibody, serca1 antibody, wu:cegs655 antibody, wu:fb17h11 antibody, wu:fb19b10 antibody, zgc:92110 antibody, ATP2A1 antibody, atp2a antibody, atp2a2 antibody, atp2b antibody, ca-p60a antibody, dar antibody, serca2 antibody, SERCA1 antibody, ATP2A3 antibody, SERCA1a antibody, Serca1 antibody, ATP2A antibody, ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 antibody, ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 antibody, ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 S homeolog antibody, atp2a1 antibody, ATP2A1 antibody, atp2a2.S antibody, Atp2a1 antibody
- 背景
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SERCA1(SARCOPLASMIC RETICULUM Ca(2+)-ATPase 1), also called ATP2A1, is an enzyme that in humans is encoded by the ATP2A1 gene. This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. The SERCA1 gene is mapped on 16p11.2. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Zhang et al.(1995)determined that the human ATP2A1 gene is 26 kb long and contains 23 exons, 1 of which can be alternatively spliced.Overexpression of S1T, but not full-length SERCA1, induced ER stress in HeLa cells and amplified ER stress through the PERK(EIF2AK3)-EIF2A -ATF4 -CHOP(DDIT3) pathway. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise.
Synonyms: fast twitch skeletal muscle isoform antibody|AT2A1_HUMAN antibody|ATP2A antibody|ATP2A1 antibody|ATPase Ca++ transporting cardiac muscle fast twitch 1 antibody|ATPase Ca++ transporting fast twitch 1 antibody|ATPase, Ca(2+)-transporting fast twitch 1 antibody|Calcium pump 1 antibody|Calcium transporting ATPase sarcoplasmic reticulum type fast twitch skeletal muscle isoform antibody|Calcium-transporting ATPase sarcoplasmic reticulum type antibody|EC 3.6.3.8 antibody|Endoplasmic reticulum class 1/2 Ca(2+) ATPase antibody|Fast skeletal muscle SR calcium ATPase antibody|fast twitch skeletal muscle isoform antibody|OTTHUMP00000162561 antibody|OTTHUMP00000162562 antibody|Sarcoendoplasmic reticulum calcium ATPase antibody|Sarcoplasmic reticulum Ca(2+)-ATPase 1 antibody|Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 antibody|SERCA 1 antibody|SERCA1 antibody|SERCA1 truncated isoform, included antibody|SR Ca(2+) ATPase 1 antibody|SR Ca(2+)-ATPase 1 antibody - UniProt
- O14983
- 途径
- Ribonucleoside Biosynthetic Process
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