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Neuregulin 2 抗体 (Middle Region)

NRG2 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044233
发货至: 中国
  • 抗原 See all Neuregulin 2 (NRG2) 抗体
    Neuregulin 2 (NRG2)
    抗原表位
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 289-306, Middle Region
    适用
    • 31
    • 8
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 31
    • 4
    克隆类型
    • 32
    • 3
    多克隆
    标记
    • 17
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Neuregulin 2 antibody is un-conjugated
    应用范围
    • 18
    • 18
    • 16
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Pro-neuregulin-2, membrane-bound isoform(NRG2) detection. Tested with WB in Human,Mouse,Rat.
    序列
    NGRKNSRLQF NKVKVEDA
    交叉反应 (详细)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Pro-neuregulin-2, membrane-bound isoform(NRG2) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: neuregulin 2
    Protein Name: Pro-neuregulin-2, membrane-bound isoform(Pro-NRG2)
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human NRG2(289-306aa NGRKNSRLQFNKVKVEDA), identical to the related rat sequence, and different from the related mouse sequence by one amino acid.
    亚型
    IgG
    Top Product
    Discover our top product NRG2 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    Neuregulin 2 (NRG2)
    别名
    NRG2 (NRG2 产品)
    别名
    NRG2 antibody, Don1 antibody, NTAK antibody, DON1 antibody, HRG2 antibody, NTAK_alpha2a antibody, Ntak antibody, neuregulin 2 antibody, NRG2 antibody, Nrg2 antibody
    背景
    Neuregulin 2, also known as NRG2, DON1 or NTAK, is a protein that in humans is encoded by the NRG2 gene. Neuregulin 2(NRG2) is a novel member of the neuregulin family of growth and differentiation factors. The NRG2 gene is mapped to 5q31.2. Through interaction with the ErbB family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The human NRG2 gene contains 12 exons and the mouse Nrg2 gene contains 12 exons and spans about 180 kb. The NRG2 genomic structure is similar to that of neuregulin 1(NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. In particular, the neuregulin-ERBB signaling pathways play crucial roles in regulating the proliferation and differentiation of Schwann cells, the myelin-forming cells in the peripheral nervous system.

    Synonyms: Divergent of neuregulin 1 antibody|Divergent of neuregulin-1 antibody|Don 1 antibody|DON-1 antibody|Neural- and thymus-derived activator for ERBB kinases antibody|Neuregulin 2 antibody|Neuregulin-2 antibody|NRG-2 antibody|Nrg2 antibody|NRG2_HUMAN antibody|NTAK antibody|Pro NRG2 antibody|Pro-NRG2 antibody
    UniProt
    O14511
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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