Neuregulin 2 抗体 (Middle Region)
Quick Overview for Neuregulin 2 抗体 (Middle Region) (ABIN3044233)
抗原
See all Neuregulin 2 (NRG2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 289-306, Middle Region
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原理
- Anti-NRG2 Antibody Picoband®
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序列
- NGRKNSRLQF NKVKVEDA
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-NRG2 Antibody (ABIN3044233). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human NRG2, identical to the related rat sequence, and different from the related mouse sequence by one amino acid.
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亚型
- IgG
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anti-Neuregulin 2 (NRG2) antibody
NRG2 适用: 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 2 (NRG2) (AA 116-215) antibodyNRG2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D2 unconjugated
anti-Neuregulin 2 (NRG2) (AA 112-405) antibodyNRG2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 2 (NRG2) antibodyNRG2 适用: 人, 大鼠, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 2 (NRG2) (Internal Region) antibodyNRG2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 2 (NRG2) (AA 358-389), (C-Term) antibodyNRG2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1278 unconjugated
anti-Neuregulin 2 (NRG2) (AA 116-215) antibodyNRG2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Neuregulin 2 (NRG2) (AA 101-211) antibodyNRG2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 2 (NRG2) (AA 618-836) antibodyNRG2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 2 (NRG2) (AA 830-855) antibodyNRG2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Britto, J. M., Lukehurst, S., Weller, R., Fraser, C., Qiu, Y., Hertzog, P., Busfield, S. J. Generation and characterization of neuregulin-2-deficient mice. Molec. Cell. Biol. 24: 8221-8226, 2004. 2. Burden, S., Yarden, Y. Neuregulins and their receptors: a versatile signaling module in organogenesis and oncogenesis. Neuron 18: 847-855, 1997. 3. Chang H, Riese DJ, Gilbert W, Stern DF, McMahan UJ (May 1997). "Ligands for ErbB-family receptors encoded by a neuregulin-like gene". -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- Neuregulin 2 (NRG2)
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别名
- NRG2
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背景
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Synonyms: Pro-neuregulin-2, membrane-bound isoform,Pro-NRG2,Neuregulin-2,NRG-2,Divergent of neuregulin-1,DON-1,Neural- and thymus-derived activator for ERBB kinases,NTAK,NRG2,NTAK,
Tissue Specificity: Restricted to the cerebellum in the adult.
Background: Neuregulin 2, also known as NRG2, DON1 or NTAK, is a protein that in humans is encoded by the NRG2 gene. Neuregulin 2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. The NRG2 gene is mapped to 5q31.2. Through interaction with the ErbB family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The human NRG2 gene contains 12 exons and the mouse Nrg2 gene contains 12 exons and spans about 180 kb. The NRG2 genomic structure is similar to that of neuregulin 1 (NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. In particular, the neuregulin-ERBB signaling pathways play crucial roles in regulating the proliferation and differentiation of Schwann cells, the myelin-forming cells in the peripheral nervous system.
Sequence Similarities: Belongs to the neuregulin family.
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分子量
- 91 kDa
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UniProt
- O14511
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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