HSD17B2 抗体 (C-Term)
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- 抗原 See all HSD17B2 抗体
- HSD17B2 (Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2))
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抗原表位
- AA 373-387, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HSD17B2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 原理
- Rabbit IgG polyclonal antibody for Estradiol 17-beta-dehydrogenase 2(HSD17B2) detection. Tested with WB, IHC-P, IHC-F in Human.
- 序列
- MPRALRMPNY KKKAT
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Estradiol 17-beta-dehydrogenase 2(HSD17B2) detection. Tested with WB, IHC-P, IHC-F in Human.
Gene Name: hydroxysteroid(17-beta) dehydrogenase 2
Protein Name: Estradiol 17-beta-dehydrogenase 2 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human HSD17B2(373-387aa MPRALRMPNYKKKAT).
- 亚型
- IgG
- Top Product
- Discover our top product HSD17B2 Primary Antibody
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anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (AA 118-387) antibody
HSD17B2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (AA 1-387) antibodyHSD17B2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (AA 373-387) antibodyHSD17B2 适用: 人 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) antibodyHSD17B2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (C-Term) antibodyHSD17B2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (AA 118-387) antibodyHSD17B2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (AA 1-387) antibodyHSD17B2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (AA 265-294) antibodyHSD17B2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26219 unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) antibodyHSD17B2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2) (AA 151-250) antibodyHSD17B2 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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- 抗原
- HSD17B2 (Hydroxysteroid (17-Beta) Dehydrogenase 2 (HSD17B2))
- 别名
- HSD17B2 (HSD17B2 产品)
- 别名
- EDH17B2 antibody, HSD17 antibody, SDR9C2 antibody, AI194836 antibody, AI194967 antibody, AI255511 antibody, hydroxysteroid 17-beta dehydrogenase 2 antibody, hydroxysteroid (17-beta) dehydrogenase 2 antibody, HSD17B2 antibody, Hsd17b2 antibody, hsd17b2 antibody
- 背景
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HSD17B2(17-BETA-HYDROXYSTEROID DEHYDROGENASE II), also called 17-BETA-HSD II, is an anzyme which have 387 amino acids with a predicted molecular weight of 42,782 and associate with the membranes of the endoplasmic reticulum. Its Cytogenetic location is 16q23.3. The type 2 enzyme was capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. HSD17B2 mRNA was detected in 18 of 42(43 % ) adenomas but not in prolactinomas. In the human endometrium, inactivation of 17-beta-estradiol to estrone is catalyzed by HSD17B2. And HSD17B2 activity distinguishing between disease-free and diseased endometria. HSD17B2 efficiently catalyzes the oxidative metabolism of androgens and estrogens, and it is expressed in a large series of human peripheral tissues. The previous paradigm that HSD17B2 activity in the endometrium is elevated during the secretory phase is confined to diseased endometrium but not to disease-free endometrium.
Synonyms: 17 beta HSD 2 antibody|17-beta-HSD 2 antibody|17-beta-hydroxysteroid dehydrogenase type 2 antibody|20 alpha HSD antibody|20 alpha hydroxysteroid dehydrogenase antibody|20 alpha-hydroxysteroid dehydrogenase antibody|20-alpha-HSD antibody|DHB2_HUMAN antibody|E2DH antibody|EDH17B2 antibody|Estradiol 17-beta-dehydrogenase 2 antibody|HSD17 antibody|Hsd17b2 antibody|Hydroxysteroid(17 beta) dehydrogenase 2 antibody|Microsomal 17 beta hydroxysteroid dehydrogenase antibody|Microsomal 17-beta-hydroxysteroid dehydrogenase antibody|SDR9C2 antibody|Testosterone 17 beta dehydrogenase antibody|Testosterone 17-beta-dehydrogenase antibody - UniProt
- P37059
- 途径
- Steroid Hormone Biosynthesis
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