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Vinculin 抗体 (N-Term)

Name: Vinculin 抗体 (N-Term)
SKU: ABIN3044168
Availability: OutOfStock

VCL 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Western Blotting (WB) image for anti-Vinculin (VCL) (AA 173-188), (N-Term) antibody (ABIN3044168) (Vinculin 抗体 (N-Term))

Anti-Vinculin antibody, IHC(P) IHC(P): Rat Intestine Tissue (Vinculin 抗体 (N-Term))

IHC

Anti-Vinculin antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue (Vinculin 抗体 (N-Term))

IHC

3 images

(6 references)

产品编号 ABIN3044168

发货至: 中国

Datasheet as PDF

抗原 See all Vinculin (VCL) 抗体

Vinculin (VCL)
抗原表位
16

9

7

6

6

5

5

4

4

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 173-188, N-Term
适用
124

86

76

28

19

5

5

5

5

3

3

2

2

2

1
人, 小鼠, 大鼠
宿主
97

28

1
兔
Compatible Secondaries
克隆类型
85

41
多克隆
标记
79

8

4

4

4

4

4

4

3

2

2

2

1

1

1

1

1

1
This Vinculin antibody is un-conjugated
应用范围
91

33

29

27

23

18

15

13

13

12

9

4

3

3

2

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for Vinculin(VCL) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

序列

KMIDERQQEL THQEHR

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Vinculin(VCL) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: vinculin
Protein Name: Vinculin

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human Vinculin(173-188aa KMIDERQQELTHQEHR), identical to the related rat and mouse sequences.

亚型

IgG

Top Product

Discover our top product VCL Primary Antibody
anti-Vinculin (VCL) (AA 1-1066) antibody
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anti-Vinculin (VCL) (AA 879-1064) antibody
VCL 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Vinculin (VCL) (AA 903-937) antibody
VCL 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB55983 unconjugated

anti-Vinculin (VCL) (AA 1020-1134) antibody
VCL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Vinculin (VCL) (AA 634-668) antibody
VCL 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB55982 unconjugated

anti-Vinculin (VCL) (AA 174-322) antibody
VCL 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal VCL-2572 unconjugated

anti-Vinculin (VCL) (AA 174-322) antibody
VCL 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal VCL-2575 unconjugated

anti-Vinculin (VCL) (AA 1-1066) antibody
VCL 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3F8-1D4 unconjugated

anti-Vinculin (VCL) (AA 767-1066) antibody
VCL 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Vinculin (VCL) antibody
VCL 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

有效期

12 months
Cong, Fu, Zhang, Zhao, Zhang: "Effects of atorvastatin on porcine aqueous humour outflow and trabecular meshwork cells." in: Experimental and therapeutic medicine, Vol. 15, Issue 1, pp. 210-216, (2018) (PubMed).

Wang, Wang, Qu, Yue, Hu, Zhang: "VEGF Enhances the Migration of MSCs in Neural Differentiation by Regulating Focal Adhesion Turnover." in: Journal of cellular physiology, Vol. 230, Issue 11, pp. 2728-42, (2015) (PubMed).

Shen, Lu, Li, Zhang, Zhu: "Synthesis and characterization of biodegradable polyurethane for hypopharyngeal tissue engineering." in: BioMed research international, Vol. 2015, pp. 871202, (2015) (PubMed).

Su, Liu, Ma, Wang, E, Liu: "Enhancement of periodontal tissue regeneration by transplantation of osteoprotegerin-engineered periodontal ligament stem cells." in: Stem cell research & therapy, Vol. 6, pp. 22, (2015) (PubMed).

Lyu, Wang, Wang, Ding, Liu, Yuan, Shi, Wang, Wang, Chen: "Maintaining the pluripotency of mouse embryonic stem cells on gold nanoparticle layers with nanoscale but not microscale surface roughness." in: Nanoscale, Vol. 6, Issue 12, pp. 6959-69, (2014) (PubMed).

Lyu, Hu, Xu, Zhang: "Dynamics of focal adhesions and reorganization of F-actin in VEGF-stimulated NSCs under varying differentiation states." in: Journal of cellular biochemistry, Vol. 114, Issue 8, pp. 1744-59, (2013) (PubMed).
抗原

Vinculin (VCL)

别名

VCL (VCL 产品)

别名

CMD1W antibody, CMH15 antibody, MV antibody, MVCL antibody, VCL antibody, im:6902790 antibody, hm:zehn2160 antibody, DDBDRAFT_0186762 antibody, DDBDRAFT_0232320 antibody, DDB_0186762 antibody, DDB_0232320 antibody, 9430097D22 antibody, AA571387 antibody, AI462105 antibody, AW545629 antibody, CG3299 antibody, CT11081 antibody, Dmel\\CG3299 antibody, Dmvincp antibody, EG:103B4.1 antibody, Vin antibody, Vin2EF antibody, vinc antibody, LOC100228062 antibody, vcl-A antibody, vinculin antibody, vinculin a antibody, vinculin A antibody, Vinculin antibody, vinculin S homeolog antibody, VCL antibody, vcla antibody, vinA antibody, Vcl antibody, Vinc antibody, CpipJ_CPIJ013873 antibody, Bm1_37935 antibody, vcl antibody, vcl.S antibody

背景

Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

Synonyms: CMD1W antibody|CMH15 antibody|Metavinculin antibody|MVCL antibody|OTTHUMP00000019861 antibody|OTTHUMP00000019862 antibody|VCL antibody|VINC antibody|VINC_HUMAN antibody|Vinculin antibody

UniProt

P18206

途径

Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2