SNRPN 抗体 (N-Term)
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- 抗原 See all SNRPN 抗体
- SNRPN (Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN))
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抗原表位
- AA 31-48, N-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SNRPN antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 原理
- Rabbit IgG polyclonal antibody for Small nuclear ribonucleoprotein-associated protein N(SNRPN) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
- 序列
- FKAFDKHMNL ILCDCDEF
- 交叉反应 （详细）
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Small nuclear ribonucleoprotein-associated protein N(SNRPN) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Gene Name: small nuclear ribonucleoprotein polypeptide N
Protein Name: Small nuclear ribonucleoprotein-associated protein N(snRNP-N) - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human SNRPN(31-48aa FKAFDKHMNLILCDCDEF), identical to the related rat and mouse sequences.
- 亚型
- IgG
- Top Product
- Discover our top product SNRPN Primary Antibody
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anti-Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN) (N-Term) antibody
SNRPN 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN) (AA 46-95) antibodySNRPN 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN) (AA 1-240) antibodySNRPN 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN) (AA 1-100) antibodySNRPN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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- 抗原
- SNRPN (Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN))
- 别名
- SNRPN (SNRPN 产品)
- 别名
- SNRB' antibody, SNRPB' antibody, Snrpn antibody, zgc:77315 antibody, HCERN3 antibody, PWCR antibody, RT-LI antibody, SM-D antibody, SMN antibody, SNRNP-N antibody, SNURF-SNRPN antibody, sm-N antibody, 2410045I01Rik antibody, Peg4 antibody, Pwcr1 antibody, FE 294 antibody, FE 294 psi antibody, FE294 antibody, FE294 psi antibody, SNURF antibody, SNRPN antibody, QflA-11237 antibody, QtrA-10022 antibody, Sm-N antibody, SmN antibody, snRNP-N antibody, small nuclear ribonucleoprotein polypeptide-like antibody, small nuclear ribonucleoprotein polypeptides B and B1 antibody, small nuclear ribonucleoprotein polypeptide N antibody, small nuclear ribonucleoprotein N antibody, small nuclear ribonucleoparticle-associated protein (snRNP) mRNA, clone Sm51 antibody, SNRPN upstream reading frame antibody, Small nuclear ribonucleoprotein-associated protein N antibody, SNRPL antibody, snrpb antibody, SNRPN antibody, Snrpn antibody, snrpn antibody, SNURF antibody
- 背景
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SNRPN(Small Nuclear Ribonucleoprotein Polypeptide N), also called SMN, is a bicistronic imprinted gene that encodes 2 polypeptides, the SmN splicing factor, which is involved in RNA processing, and the SNRPN upstream reading frame(SNURF) polypeptide. The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. SNRPN also encodes a long alternatively spliced transcript containing several small nucleolar RNAs(snoRNAs) and extends downstream to partially overlap the UBE3A gene in the antisense orientation. PWS arises from loss of function of genes in this region expressed exclusively from the paternal chromosome, suggesting that SNRPN may play a role in its etiology. The SNRPN gene is mapped on 15q11.2. Analysis of maternal DNA and of SNRPN cDNA confirmed that the maternal allele is not expressed in fetal brain and heart. Deletions in the transcription unit of the imprinted SNRPN gene occur in patients who have PWS or Angelman syndrome because of a parental imprint switch failure in this chromosomal domain.
Synonyms: HCERN3 antibody|PWCR antibody|RSMN_HUMAN antibody|RT LI antibody|RTLI antibody|SM D antibody|Sm N antibody|Sm protein D antibody|Sm protein N antibody|Sm-D antibody|Sm-N antibody|Small nuclear ribonucleoprotein associated protein N antibody|Small nuclear ribonucleoprotein polypeptide N antibody|Small nuclear ribonucleoprotein-associated protein N antibody|SMD antibody|SmN antibody|SNRNP N antibody|snRNP-N antibody|SNRNPN antibody|SNRPN antibody|SNURF SNRPN antibody|Tissue specific splicing protein antibody|Tissue-specific-splicing protein antibody - UniProt
- P63162
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