电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

NRP2 抗体 (N-Term)

NRP2 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044160
发货至: 中国
  • 抗原 See all NRP2 抗体
    NRP2 (Neuropilin 2 (NRP2))
    抗原表位
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 45-60, N-Term
    适用
    • 46
    • 24
    • 19
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    大鼠
    宿主
    • 50
    • 3
    克隆类型
    • 51
    • 2
    多克隆
    标记
    • 26
    • 7
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NRP2 antibody is un-conjugated
    应用范围
    • 39
    • 23
    • 11
    • 5
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Neuropilin-2(NRP2) detection. Tested with WB in Human,Mouse,Rat.
    序列
    YPQDYPSHQN CEWIVY
    交叉反应 (详细)
    Predicted Cross Reactivity: human, mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Neuropilin-2(NRP2) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: neuropilin 2
    Protein Name: Neuropilin-2
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human NRP2(45-60aa YPQDYPSHQNCEWIVY), identical to the related mouse sequence and different from the related rat sequence by one amino acid.
    亚型
    IgG
    Top Product
    Discover our top product NRP2 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    NRP2 (Neuropilin 2 (NRP2))
    别名
    NRP2 (NRP2 产品)
    别名
    NP2 antibody, NPN2 antibody, PRO2714 antibody, VEGF165R2 antibody, 1110048P06Rik antibody, Np-2 antibody, Np2 antibody, Npn-2 antibody, Npn2 antibody, neuropilin-2 antibody, neuropilin 2 antibody, NRP2 antibody, Nrp2 antibody
    背景
    NRP2(Neuropilin-2), also called Npn2 or VEGF165R2, encodes a member of the neuropilin family of receptor proteins. The soluble NRP2 was secreted as a 62.5-kD protein following transfection in Chinese hamster ovary cells. The NRP2 gene is mapped on 2q33.3. The NRP2 gene contains 17 exons and spans about 112 kb. Sema3b can act to repulse axons expressing neuropilin-2 and can antagonize the repulsive action of Sema3a on axonal growth cones expressing neuropilin-1. This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Mice with null mutations in genes encoding Sema3F, and its holoreceptor components Npn2 and plexin A3(PLEXA3), exhibit increased dentate gyrus granule cell and cortical layer V pyramidal neuron spine number and size, and also aberrant spine distribution. Moreover, Sema3F promotes loss of spines and excitatory synapses in dissociated neurons in vitro, and in Npn2-null brain slices cortical layer V and dentate gyrus granule cells exhibit increased miniature excitatory postsynaptic current frequency. These disparate effects of secreted semaphorins are reflected in the restricted dendritic localization of Npn2 to apical dendrites and of Npn1 to all dendrites of cortical pyramidal neurons.

    Synonyms: MGC126574 antibody|Neuropilin 2 antibody|Neuropilin-2 antibody|Neuropilin2 antibody|NP 2 antibody|NP2 antibody|NPN 2 antibody|NPN2 antibody|NRP 2 antibody|Nrp2 antibody|NRP2_HUMAN antibody|PRO2714 antibody|Receptor for VEGF165 and semaphorins class3 antibody|Vascular endothelial cell growth factor 165 receptor 2 antibody|Vascular endothelial growth factor 165 receptor 2 antibody|VEGF1265R2 antibody|VEGF165R2 antibody
    UniProt
    O60462
    途径
    Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
You are here:
客服