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- 抗原 See all p107 (RBL1) 抗体
- p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))
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抗原表位
- AA 1048-1068, C-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This p107 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Retinoblastoma-like protein 1(RBL1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- QENDDVLLKR LQDVVSERAN H
- 交叉反应 （详细）
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Retinoblastoma-like protein 1(RBL1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: retinoblastoma-like 1(p107)
Protein Name: Retinoblastoma-like protein 1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human p107(1048-1068aa QENDDVLLKRLQDVVSERANH), identical to the related rat and mouse sequences.
- 亚型
- IgG
- Top Product
- Discover our top product RBL1 Primary Antibody
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anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 905-1014) antibody
RBL1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1A5 unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 1007-1035), (C-Term) antibodyRBL1 适用: 人 WB 宿主: 兔 Polyclonal RB40387 unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 1-1014) antibodyRBL1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (C-Term) antibodyRBL1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (pSer975) antibodyRBL1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7537 unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (pSer975) antibodyRBL1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 201-500) antibodyRBL1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 143-192) antibodyRBL1 适用: 人, 小鼠, 马, Pig, Cow, 犬, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 935-984) antibodyRBL1 适用: 人, 小鼠, 大鼠, 马, Pig, Cow, 犬, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoblastoma-Like 1 (p107) (RBL1) (AA 100-200) antibodyRBL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, The detection limit for RBL1 is approximately 2.5 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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- 抗原
- p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))
- 别名
- RBL1 (RBL1 产品)
- 别名
- p107 antibody, prb1 antibody, fj58e06 antibody, wu:fj58e06 antibody, CP107 antibody, PRB1 antibody, AW547426 antibody, retinoblastoma-like 1 L homeolog antibody, RB transcriptional corepressor like 1 antibody, retinoblastoma-like 1 (p107) antibody, retinoblastoma-like 1 antibody, rbl1.L antibody, RBL1 antibody, rbl1 antibody, Rbl1 antibody
- 背景
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RBL1(Retinoblastoma-like 1), also known as Cullular Proteins p107, CP107 and 107, is a protein that in humans is encoded by the RBL1 gene. Ewen et al.(1991)used a partial cDNA for human p107 to map the gene to 20q11. by fluorescence in situ hybridization. Huppi et al.(1996)found that the mouse Rbl1 gene maps to the distal end of chromosome 2, as does also the E2f1 gene. The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1(RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 Large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is though that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms: 107 kDa retinoblastoma associated protein antibody|107 kDa retinoblastoma-associated protein antibody|Cellular protein 107 antibody|Cellular protein p107 antibody|CP 107 antibody|CP107 antibody|MGC40006 antibody|p107 antibody|PRB 1 antibody|PRB1 antibody|RB L1 antibody|RBL 1 antibody|RBL1 antibody|RBL1_HUMAN antibody|Retinoblastoma like 1 antibody|Retinoblastoma like protein 1 antibody|retinoblastoma-like 1(p107) antibody|Retinoblastoma-like protein 1 antibody - UniProt
- P28749
- 途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
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