(2 references)-
- 抗原 See all ABCG1 抗体
- ABCG1 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1))
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抗原表位
- AA 627-647, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ABCG1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family G member 1(ABCG1) detection. Tested with WB in Human,Mouse,Rat.
- 序列
- ETCHFQKSEA ILRELDVENA K
- 交叉反应 （详细）
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Predicted Cross Reactivity: mouse, rat
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family G member 1(ABCG1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: ATP-binding cassette, sub-family G(WHITE), member 1
Protein Name: ATP-binding cassette sub-family G member 1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human ABCG1(627-647aa ETCHFQKSEAILRELDVENAK), identical to the related rat and mouse sequences.
- 亚型
- IgG
- Top Product
- Discover our top product ABCG1 Primary Antibody
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anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1) (AA 1-220) antibody
ABCG1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1) (AA 168-195) antibodyABCG1 适用: 人, 小鼠 WB, IHC, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1) (AA 79-312) antibodyABCG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1) (C-Term) antibodyABCG1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1) (AA 168-195), (N-Term) antibodyABCG1 适用: 人, 小鼠 WB, FACS, IHC (p), IF 宿主: 兔 Polyclonal RB19678 unconjugated
anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1) (AA 561-678) antibodyABCG1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1) (AA 21-130) antibodyABCG1 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 2H8 unconjugated
anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1) (AA 359-387) antibodyABCG1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19679 unconjugated
anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1) (AA 359-387) antibodyABCG1 适用: 人 IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1) (C-Term) antibodyABCG1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, The detection limit for ABCG1 is approximately 5 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
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: "Fibroblast growth factor 21 enhances cholesterol efflux in THP-1 macrophage-derived foam cells." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 503-8, (2014) (PubMed).
: "Sphingomyelin synthase overexpression increases cholesterol accumulation and decreases cholesterol secretion in liver cells." in: Lipids in health and disease, Vol. 10, pp. 46, (2011) (PubMed).
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: "Fibroblast growth factor 21 enhances cholesterol efflux in THP-1 macrophage-derived foam cells." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 503-8, (2014) (PubMed).
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- 抗原
- ABCG1 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1))
- 别名
- ABCG1 (ABCG1 产品)
- 别名
- ABCG1 antibody, zgc:162197 antibody, ABC8 antibody, WHITE1 antibody, AW413978 antibody, Abc8 antibody, White antibody, ATP binding cassette subfamily G member 1 antibody, ATP-binding cassette, sub-family G (WHITE), member 1 antibody, ABCG1 antibody, abcg1 antibody, Abcg1 antibody
- 背景
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ABCG1(Atp-binding cassette, subfamily g, member 1) also known as ABC8, ABC TRANSPORTER 8 or WHITE, DROSOPHILA, HOMOLOG OF, is a protein that in humans is encoded by the ABCG1 gene. ABCG1 is a regulator of macrophage cholesterol and phospholipid transport. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette(ABC) transporters.The ABCG1 gene is mapped on 21q22.3. This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. ABCG1 is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. Inhibition of ABCG1 protein expression using an antisense strategy resulted in reduced HDL3-dependent efflux of cholesterol and choline-phospholipids. In macrophages, silencing of GPS2 by RNA interference reduced ABCG1 expression and diminished ABCG1-mediated cholesterol efflux.
Synonyms: ABC transporter 8 antibody|Abc8 antibody|ABCG1 antibody|ABCG1_HUMAN antibody|ATP-binding cassette sub family G member 1 antibody|ATP-binding cassette sub-family G member 1 antibody|ATP-binding cassette transporter 8 antibody|ATP-binding cassette transporter member 1 of subfamily G antibody|ATP-binding cassette, sub family G WHITE member 1 antibodyhomolog of Drosophila white antibody|MGC34313 antibody|White protein homolog antibody|White protein homolog ATP binding cassette transporter 8 antibody|WHITE1 antibody|wht1 antibody - UniProt
- P45844
- 途径
- Lipid Metabolism
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