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TRAM2 抗体 (C-Term)

TRAM2 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044050
发货至: 中国
  • 抗原 See all TRAM2 抗体
    TRAM2 (Translocation Associated Membrane Protein 2 (TRAM2))
    抗原表位
    • 9
    • 8
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 309-325, C-Term
    适用
    • 33
    • 14
    • 12
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    小鼠
    宿主
    • 33
    • 1
    克隆类型
    • 33
    • 1
    多克隆
    标记
    • 13
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRAM2 antibody is un-conjugated
    应用范围
    • 22
    • 19
    • 14
    • 3
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Translocating chain-associated membrane protein 2(TRAM2) detection. Tested with WB in Human,Mouse,Rat.
    序列
    RFIHSQLRHW REYWKEQ
    交叉反应 (详细)
    Predicted Cross Reactivity: human, rat
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Translocating chain-associated membrane protein 2(TRAM2) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: translocation associated membrane protein 2
    Protein Name: Translocating chain-associated membrane protein 2
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of mouse TRAM2(309-325aa RFIHSQLRHWREYWKEQ), identical to the related rat sequence, and different from the related human sequence by one amino acid.
    亚型
    IgG
    Top Product
    Discover our top product TRAM2 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Predicted Species: Human, Rat, The detection limit for TRAM2 is approximately 5 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    TRAM2 (Translocation Associated Membrane Protein 2 (TRAM2))
    别名
    TRAM2 (TRAM2 产品)
    别名
    C330003D03Rik antibody, wu:fb20c11 antibody, wu:fi23a12 antibody, zgc:111902 antibody, zgc:55869 antibody, zgc:76937 antibody, tram2 antibody, translocation associated membrane protein 2 antibody, tram-like protein antibody, TraM-like protein antibody, translocating chain-associating membrane protein 2 antibody, translocation associated membrane protein 2 L homeolog antibody, TRAM2 antibody, CJE0444 antibody, BT_p548215 antibody, traM antibody, CJJ81176_0418 antibody, Tram2 antibody, tram2 antibody, tram2.L antibody
    背景
    TRAM2(Translocation-Associating Membrane Protein 2), also called KIAA0057, is a protein that in humans is encoded by the TRAM2 gene. TRAM2 is a component of the translocon, a gated macromolecular channel that controls the posttranslational processing of nascent secretory and membrane proteins at the endoplasmic reticulum(ER) membrane. By genomic sequence analysis, Onuchic et al.(1999) mapped the TRAM2 gene to chromosome 6p21.1-p12 near the PKHD1 gene. Upon activation, quiescent hepatic stellate cells proliferate, change morphologically into myofibroblasts, and increase their synthesis of extracellular matrix proteins. Stefanovic et al.(2004) demonstrated that both TRAM2 and collagen type I are upregulated in activated rat and human hepatic stellate cells.

    Synonyms: C330003D03Rik antibody|KIAA0057 antibody|MGC25725 antibody|OTTHUMP00000016607 antibody|TRAM like protein antibody|Tram2 antibody|TRAM2_HUMAN antibody|Translocating chain associating membrane protein 2 antibody|Translocating chain-associated membrane protein 2 antibody|Translocation associated membrane protein 2 antibody
    UniProt
    Q924Z5
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