Tec Protein Tyrosine Kinase (TEC) (AA 612-631), (C-Term) 抗体
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Quick Overview for Tec Protein Tyrosine Kinase (TEC) (AA 612-631), (C-Term) 抗体 (ABIN3044046)
抗原
See all Tec Protein Tyrosine Kinase (TEC) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 612-631, C-Term
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原理
- Anti-Tyrosine-protein kinase Tec Tec Antibody
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序列
- FEDLLRTIDE LVECEETFGR
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Tyrosine-protein kinase Tec Tec Antibody (ABIN3044046). Tested in IHC, WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Tec, identical to the related rat sequence, and different from the related mouse sequence by one amino acid.
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亚型
- IgG
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anti-Tec Protein Tyrosine Kinase (TEC) (AA 1-280) antibody
TEC 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tec Protein Tyrosine Kinase (TEC) (AA 175-205) antibodyTEC 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB03266 unconjugated
anti-Tec Protein Tyrosine Kinase (TEC) (AA 612-631) antibodyTEC 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tec Protein Tyrosine Kinase (TEC) (AA 370-623) antibodyTEC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tec Protein Tyrosine Kinase (TEC) antibodyTEC 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3A5 unconjugated
anti-Tec Protein Tyrosine Kinase (TEC) antibodyTEC 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4520 unconjugated Recombinant Antibody
anti-Tec Protein Tyrosine Kinase (TEC) (AA 503-552) antibodyTEC 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 猴, 小鸡, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Tec Protein Tyrosine Kinase (TEC) (AA 254-288) antibodyTEC 适用: 人 WB 宿主: 兔 Polyclonal RB51015 unconjugated
anti-Tec Protein Tyrosine Kinase (TEC) (AA 369-622) antibodyTEC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tec Protein Tyrosine Kinase (TEC) (Middle Region) antibodyTEC 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat
Western blot, 0.1-0.5 μg/mL, Human, Rat
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Thimerosal, 0.01 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- Tec Protein Tyrosine Kinase (TEC)
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别名
- TEC
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背景
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Synonyms: Tyrosine-protein kinase Tec,2.7.10.2,TEC,PSCTK4,
Tissue Specificity: Expressed in a wide range of cells, including hematopoietic cell lines like myeloid, B-, and T-cell lineages.
Background: TEC (TEC Protein Tyrosine Kinase), is an enzyme that in humans is encoded by the TEC gene. The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. By fluorescence in situ hybridization, Sato et al. (1994) mapped the gene to 4p12, the same location reported for TXK. Mouse Tec is a non-receptor type protein-tyrosine kinase that is highly expressed in many hematopoietic cell lines. Hantschel et al. (2007) identified TEC kinase and BTK kinase as major binders of the tyrosine kinase inhibitor dasatinib, which is used for treatment of BCR/ABL-positive CML.
Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily.
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分子量
- 58-60 kDa
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UniProt
- P42680
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途径
- Fc-epsilon Receptor Signaling Pathway
抗原
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