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Tec Protein Tyrosine Kinase (TEC) (AA 612-631) 抗体

The 兔 多克隆 anti-Tec Protein Tyrosine Kinase antibody is suitable to detect Tec Protein Tyrosine Kinase in samples from 人 和 大鼠. It has been validated for WB 和 IHC (p).
产品编号 ABIN3032066
发货至: 中国
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Quick Overview for Tec Protein Tyrosine Kinase (TEC) (AA 612-631) 抗体 (ABIN3032066)

抗原

See all Tec Protein Tyrosine Kinase (TEC) 抗体
Tec Protein Tyrosine Kinase (TEC)

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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非结合性

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    AA 612-631

    纯化方法

    Antigen affinity

    免疫原

    Amino acids 612-631 (FEDLLRTIDELVECEETFGR-human) were used as the immunogen for this Tec antibody (100% rat homology).

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the Tec antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the Tec antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    Tec Protein Tyrosine Kinase (TEC)

    别名

    Tec

    背景

    TEC Protein Tyrosine Kinase, is an enzyme that in humans is encoded by the TEC gene. The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. By fluorescence in situ hybridization, Sato et al.(1994) mapped the gene to 4p12, the same location reported for TXK. Mouse Tec is a non-receptor type protein-tyrosine kinase that is highly expressed in many hematopoietic cell lines. Hantschel et al.(2007) identified TEC kinase and BTK kinase as major binders of the tyrosine kinase inhibitor dasatinib, which is used for treatment of BCR/ABL-positive CML.

    UniProt

    P42680

    途径

    Fc-epsilon Receptor Signaling Pathway
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