Tec Protein Tyrosine Kinase (TEC) (AA 612-631) 抗体
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Quick Overview for Tec Protein Tyrosine Kinase (TEC) (AA 612-631) 抗体 (ABIN3032066)
抗原
See all Tec Protein Tyrosine Kinase (TEC) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 612-631
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纯化方法
- Antigen affinity
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免疫原
- Amino acids 612-631 (FEDLLRTIDELVECEETFGR-human) were used as the immunogen for this Tec antibody (100% rat homology).
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亚型
- IgG
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the Tec antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the Tec antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Tec Protein Tyrosine Kinase (TEC)
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别名
- Tec
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背景
- TEC Protein Tyrosine Kinase, is an enzyme that in humans is encoded by the TEC gene. The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. By fluorescence in situ hybridization, Sato et al.(1994) mapped the gene to 4p12, the same location reported for TXK. Mouse Tec is a non-receptor type protein-tyrosine kinase that is highly expressed in many hematopoietic cell lines. Hantschel et al.(2007) identified TEC kinase and BTK kinase as major binders of the tyrosine kinase inhibitor dasatinib, which is used for treatment of BCR/ABL-positive CML.
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UniProt
- P42680
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途径
- Fc-epsilon Receptor Signaling Pathway
抗原
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