Tec Protein Tyrosine Kinase (TEC) 抗体
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北京 101111
Quick Overview for Tec Protein Tyrosine Kinase (TEC) 抗体 (ABIN969434)
抗原
See all Tec Protein Tyrosine Kinase (TEC) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- TEC Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of TEC expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Identification and characterization of a bacterial transport system for the uptake of pyruvate, propionate, and acetate in Corynebacterium glutamicum." in: Journal of bacteriology, Vol. 191, Issue 3, pp. 940-8, (2009) (PubMed).
: "Stem cell factor induces phosphatidylinositol 3'-kinase-dependent Lyn/Tec/Dok-1 complex formation in hematopoietic cells." in: Blood, Vol. 96, Issue 10, pp. 3406-13, (2000) (PubMed).
: "Cef1p is a component of the Prp19p-associated complex and essential for pre-mRNA splicing." in: The Journal of biological chemistry, Vol. 274, Issue 14, pp. 9455-62, (1999) (PubMed).
: "Expression and activation of the nonreceptor tyrosine kinase Tec in human B cells." in: Blood, Vol. 91, Issue 3, pp. 940-8, (1998) (PubMed).
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- Tec Protein Tyrosine Kinase (TEC)
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别名
- TEC
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背景
- TEC, it belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
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分子量
- 74 kDa
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UniProt
- P42680
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途径
- Fc-epsilon Receptor Signaling Pathway
抗原
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