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MFGE8 抗体 (Middle Region)

MFGE8 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044017
发货至: 中国
  • 抗原 See all MFGE8 抗体
    MFGE8 (Milk Fat Globule-EGF Factor 8 Protein (MFGE8))
    抗原表位
    • 15
    • 9
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 165-180, Middle Region
    适用
    • 62
    • 10
    • 4
    • 3
    宿主
    • 44
    • 22
    • 4
    • 1
    克隆类型
    • 48
    • 23
    多克隆
    标记
    • 44
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MFGE8 antibody is un-conjugated
    应用范围
    • 60
    • 24
    • 21
    • 20
    • 13
    • 13
    • 11
    • 11
    • 11
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Lactadherin(MFGE8) detection. Tested with WB, IHC-P in Human.
    序列
    NGHEFDFIHD VNKKHK
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Lactadherin(MFGE8) detection. Tested with WB, IHC-P in Human.
    Gene Name: milk fat globule-EGF factor 8 protein
    Protein Name: Lactadherin
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human Human Milk Fat Globule 1(165-180aa NGHEFDFIHDVNKKHK).
    亚型
    IgG
    Top Product
    Discover our top product MFGE8 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for MFGE8 is approximately 0.5 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • Becker-Dreps, Choi, Stamper, Vilchez, Velasquez, Moon, Hudgens, Jiang, Permar: "Innate Immune Factors in Mothers' Breast Milk and Their Lack of Association With Rotavirus Vaccine Immunogenicity in Nicaraguan Infants." in: Journal of the Pediatric Infectious Diseases Society, Vol. 6, Issue 1, pp. 87-90, (2018) (PubMed).

  • 抗原
    MFGE8 (Milk Fat Globule-EGF Factor 8 Protein (MFGE8))
    别名
    MFGE8 (MFGE8 产品)
    别名
    BA46 antibody, EDIL1 antibody, HMFG antibody, HsT19888 antibody, MFG-E8 antibody, MFGM antibody, OAcGD3S antibody, SED1 antibody, SPAG10 antibody, hP47 antibody, ba46 antibody, edil1 antibody, oacgd3s antibody, MGC75581 antibody, hst19888 antibody, MGC145109 antibody, MFGE8 antibody, mfge8 antibody, zgc:154157 antibody, MGC99228 antibody, AA408458 antibody, AI325141 antibody, Mfgm antibody, P47 antibody, lactadherin antibody, AGS antibody, MFGME8 antibody, MFGMP-E8 antibody, im:6895406 antibody, mfge8l antibody, zgc:110846 antibody, milk fat globule-EGF factor 8 protein antibody, milk fat globule-EGF factor 8 protein b antibody, milk fat globule-EGF factor 8 protein L homeolog antibody, milk fat globule-EGF factor 8 protein a antibody, MFGE8 antibody, mfge8 antibody, mfge8b antibody, mfge8.L antibody, Mfge8 antibody, mfge8a antibody
    背景
    MFGE8(Milk Fat Globule-Egf Factor 8), also called as Lactadherin or SED1, is a protein which in humans is encoded by the MFGE8 gene. Mfge8 is secreted protein found in vertebrates, including mammals as well as birds. By fluorescence in situ hybridization, Collins et al.(1997) mapped the MFGE8 gene to chromosome 15q25. Hanayama et al.(2002) found that MFGE8 is a factor that links apoptotic cells to phagocytes. MFGE8 specifically bound to apoptotic cells by recognizing aminophospholipids such as phosphatidylserine. MFGE8, when engaged by phospholipids, bound to cells via its RGD motif. It bound particularly strongly to cells expressing alpha-V-beta-3 integrin. Bu et al.(2007) showed that Mfge8 was expressed in intestinal lamina propria macrophages in mice. Using a wound-healing assay, they showed that Mfge8 promoted migration of intestinal epithelial cells through a PKC-epsilon(PRKCE)-dependent mechanism.

    Synonyms: BA 46 antibody|BA46 antibody|Breast epithelial antigen BA46 antibody|Contains Medin antibody|EDIL 1 antibody|EDIL1 antibody|HMFG antibody|hP47 antibody|HsT19888 antibody|Lactadherin antibody|Lactadherin precursor antibody|Medin antibody|MFG E8 antibody|MFG-E8 antibody|MFGE 8 antibody|MFGE8 antibody|MFGE8 protein antibody|MFGM antibody|MFGM_HUMAN antibody|Milk fat globule EGF factor 8 antibody|Milk fat globule EGF factor 8 protein antibody|Milk fat globule-EGF factor 8 antibody|O acetyl disialoganglioside synthase antibody|OAcGD3S antibody|SED1 antibody|SPAG10 antibody|Sperm associated antigen 10 antibody|Sperm surface protein hP47 antibody
    UniProt
    Q08431
    途径
    SARS-CoV-2 Protein Interactome
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