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P2RX5 抗体 (AA 333-422)

P2RX5 适用: 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043894
发货至: 中国
  • 抗原 See all P2RX5 抗体
    P2RX5 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 5 (P2RX5))
    抗原表位
    • 14
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 333-422
    适用
    • 32
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    大鼠, 小鼠
    宿主
    • 27
    • 5
    克隆类型
    • 30
    • 2
    多克隆
    标记
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    This P2RX5 antibody is un-conjugated
    应用范围
    • 32
    • 17
    • 15
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for P2X purinoceptor 5(P2RX5) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    交叉反应 (详细)
    Predicted Cross Reactivity: human
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for P2X purinoceptor 5(P2RX5) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: purinergic receptor P2X, ligand gated ion channel, 5
    Protein Name: P2X purinoceptor 5
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human P2X5 recombinant protein (Position: D333-T422). Human P2X5 shares 42% amino acid (aa) sequence identity with rat P2X5.
    亚型
    IgG
    Top Product
    Discover our top product P2RX5 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human, The detection limit for P2X5 is approximately 0.25 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Meng, Zheng, Yan, Li, Fang, Li: "P2X2 and P2X5 Receptors Mediate Bladder Hyperesthesia in ICC in Female Overactive Bladder." in: Cell biochemistry and biophysics, Vol. 72, Issue 2, pp. 375-83, (2016) (PubMed).

  • 抗原
    P2RX5 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 5 (P2RX5))
    别名
    P2RX5 (P2RX5 产品)
    别名
    P2RX5 antibody, LRH-1 antibody, P2X5 antibody, P2X5R antibody, P2x5 antibody, purinergic receptor P2X 5 antibody, purinergic receptor P2X, ligand-gated ion channel, 5 antibody, P2RX5 antibody, P2rx5 antibody
    背景
    P2X purinoceptor 5 is a protein that in humans is encoded by the P2RX5 gene. The product of this gene belongs to the family of purinoceptors for ATP. It has been identified that the P2RX5 gene within a BAC contig covering chromosome 17p13. This receptor functions as a ligand-gated ion channel. Several characteristic motifs of ATP-gated channels are present in its primary structure, but, unlike other members of the purinoceptors family, this receptor has only a single transmembrane domain. Quantitative dot blots revealed that P2X5R expression is highest in brain and immune system and is developmentally regulated.

    Synonyms: ATP receptor antibody|ATP receptor subunit antibody|Ionotropic ATP receptor P2X5 antibody|LRH 1 antibody|LRH1 antibody|Lymphoid restricted histocompatibility antigen 1 antibody|MGC47755 antibody|P2rx5 antibody|P2RX5_HUMAN antibody|P2X purinoceptor 5 antibody|P2X5 antibody|P2X5R antibody|Purinergic receptor antibody|Purinergic receptor P2X ligand gated ion channel 5 antibody|Purinergic receptor P2X5 antibody
    基因ID
    5026
    UniProt
    Q93086
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