IDH2 抗体 (C-Term)
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- 抗原 See all IDH2 抗体
- IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))
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抗原表位
- AA 413-447, C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IDH2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for Isocitrate dehydrogenase [NADP], mitochondrial(IDH2) detection. Tested with WB, IHC-P in Human, Mouse,Rat.
- 序列
- KDLAGCIHGL SNVKLNEHFL NTTDFLDTIK SNLDR
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Isocitrate dehydrogenase [NADP], mitochondrial(IDH2) detection. Tested with WB, IHC-P in Human, Mouse,Rat.
Gene Name: isocitrate dehydrogenase 2 (NADP+), mitochondrial
Protein Name: Isocitrate dehydrogenase [NADP], mitochondrial - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human IDH2 (413-447aa KDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDR), identical to the related mouse and rat sequences.
- 亚型
- IgG
- Top Product
- Discover our top product IDH2 Primary Antibody
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anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 40-452) antibody
IDH2 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 193-452) antibodyIDH2 适用: 人 WB, IP, IF, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 1-143) antibodyIDH2 适用: 人 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 3E8E9 unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 354-451) antibodyIDH2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5F11 unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 354-452) antibodyIDH2 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5F11 unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (Middle Region) antibodyIDH2 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 马, 斑马鱼, 豚鼠, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 251-350) antibodyIDH2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 193-452) antibodyIDH2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (Internal Region) antibodyVerified IDH2 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) (AA 354-451) antibodyIDH2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))
- 别名
- IDH2 (IDH2 产品)
- 别名
- F6P23.14 antibody, F6P23_14 antibody, IDH-II antibody, NAD+ DEPENDENT ISOCITRATE DEHYDROGENASE SUBUNIT 2 antibody, isocitrate dehydrogenase II antibody, isocitrate dehydrogenase subunit 2 antibody, D2HGA2 antibody, ICD-M antibody, IDH antibody, IDHM antibody, IDP antibody, IDPM antibody, mNADP-IDH antibody, E430004F23 antibody, IDPm antibody, Idh-2 antibody, wu:fb33c06 antibody, wu:fk31e05 antibody, wu:fq43b01 antibody, zgc:55485 antibody, idh2 antibody, IDH2 antibody, isocitrate dehydrogenase subunit 2 antibody, isocitrate dehydrogenase (NADP(+)) 2, mitochondrial antibody, isocitrate dehydrogenase 2 (NADP+), mitochondrial antibody, isocitrate dehydrogenase 2 (NADP+), mitochondrial S homeolog antibody, isocitrate dehydrogenase [NADP], mitochondrial antibody, IDH2 antibody, Idh2 antibody, idh2.S antibody, idh2 antibody, LOC100441867 antibody
- 背景
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Isocitrate dehydrogenase [NADP], mitochondrial is an enzyme that in humans is encoded by the IDH2 gene. Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.
Synonyms: D2HGA2 antibody|ICD-M antibody|IDH antibody|IDH2 antibody|IDHM antibody|IDHP_HUMAN antibody|IDP antibody|IDPM antibody|Isocitrate dehydrogenase [NADP], mitochondrial antibody|Isocitrate dehydrogenase 2 (NADP+), mitochondrial antibody|mNADP-IDH antibody|NADP(+)-specific ICDH antibody|Oxalosuccinate decarboxylase antibody - 基因ID
- 3418
- UniProt
- P48735
- 途径
- Warburg Effect
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