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ATP2A3 抗体 (N-Term)

ATP2A3 适用: 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043794
发货至: 中国
  • 抗原 See all ATP2A3 抗体
    ATP2A3 (ATPase, Ca++ Transporting, Ubiquitous (ATP2A3))
    抗原表位
    • 15
    • 1
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    AA 1-30, N-Term
    适用
    • 24
    • 15
    • 15
    • 4
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    • 2
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    • 1
    小鼠, 大鼠
    宿主
    • 23
    • 2
    克隆类型
    • 23
    • 2
    多克隆
    标记
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This ATP2A3 antibody is un-conjugated
    应用范围
    • 24
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Sarcoplasmic/endoplasmic reticulum calcium ATPase 3(ATP2A3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    序列
    MEAAHLLPAA DVLRHFSVTA EGGLSPAQVT
    交叉反应 (详细)
    Predicted Cross Reactivity: human
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Sarcoplasmic/endoplasmic reticulum calcium ATPase 3(ATP2A3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: ATPase, Ca++ transporting, ubiquitous
    Protein Name: Sarcoplasmic/endoplasmic reticulum calcium ATPase 3
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human ATP2A3(1-30aa MEAAHLLPAADVLRHFSVTAEGGLSPAQVT), different from the related mouse sequence by five amino acids, and from the related rat sequence by six amino acids.
    亚型
    IgG
    Top Product
    Discover our top product ATP2A3 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    ATP2A3 (ATPase, Ca++ Transporting, Ubiquitous (ATP2A3))
    别名
    ATP2A3 (ATP2A3 产品)
    别名
    serca3 antibody, si:dkey-205l20.1 antibody, ATP2A3 antibody, Atp2a3 antibody, SERCA3 antibody, SERCA3b antibody, Serca3 antibody, SERCA antibody, ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 L homeolog antibody, ATPase, Ca++ transporting, ubiquitous antibody, ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 antibody, atp2a3.L antibody, atp2a3 antibody, ATP2A3 antibody, Atp2a3 antibody
    背景
    Sarcoplasmic/endoplasmic reticulum calcium ATPase 3, also known as SERCA3, is anenzyme that in humans is encoded by the ATP2A3 gene. It is mapped to 17p13.2. This gene encodes one of the SERCA Ca2+-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of cells. ATP2A3 expression was originally described as non-muscular, but was recently observed in cardiomyocyte. What's more, the expression of ATP2A3 was significantly reduced or lost in colon carcinomas compared with normal colonic epithelial cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction.

    Synonyms: Adenosine triphosphatase calcium antibody|AT2A3_HUMAN antibody|ATP2A3 antibody|ATPase Ca(2+) transporting ubiquitous antibody|ATPase Ca++ transporting ubiquitous antibody|Calcium pump 3 antibody|Calcium translocating P type ATPase antibody|Sarco/endoplasmic reticulum Ca2+ ATPase antibody|Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 antibody|SERCA 3 antibody|SERCA3 antibody|SERCA3b antibody|SR Ca(2+) ATPase 3 antibody|SR Ca(2+)-ATPase 3 antibody
    基因ID
    489
    UniProt
    Q93084
    途径
    Myometrial Relaxation and Contraction, Ribonucleoside Biosynthetic Process
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