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APLP1 抗体 (N-Term)

APLP1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043786
发货至: 中国
  • 抗原 See all APLP1 抗体
    APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
    抗原表位
    • 15
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 82-112, N-Term
    适用
    • 33
    • 31
    • 15
    • 6
    • 5
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 44
    • 2
    克隆类型
    • 45
    • 1
    多克隆
    标记
    • 13
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APLP1 antibody is un-conjugated
    应用范围
    • 32
    • 13
    • 13
    • 8
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Amyloid-like protein 1(APLP1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    序列
    RRCLRDPQRV LEYCRQMYPE LQIARVEQAT Q
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Amyloid-like protein 1(APLP1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: amyloid beta (A4) precursor-like protein 1
    Protein Name: Amyloid-like protein 1
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human APLP1 (82-112aa RRCLRDPQRVLEYCRQMYPELQIARVEQATQ), different from the related mouse sequence by three amino acids.
    亚型
    IgG
    Top Product
    Discover our top product APLP1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    APLP1 (Amyloid beta (A4) Precursor-Like Protein 1 (APLP1))
    别名
    APLP1 (APLP1 产品)
    别名
    aplp antibody, MGC115336 antibody, APLP antibody, Aplp1_retired antibody, RGD1561211 antibody, amyloid beta precursor like protein 1 antibody, amyloid beta precursor like protein 1 L homeolog antibody, amyloid beta (A4) precursor-like protein 1 antibody, APLP1 antibody, aplp1.L antibody, aplp1 antibody, Aplp1 antibody
    背景
    Amyloid-precursor-like protein 1 (APLP1) is a membrane-associated glycoprotein, whose gene is homologous to the APP gene, which has been shown to be involved in the pathogenesis of Alzheimer's disease. APLP1 is predominantly expressed in brain, particularly in the cerebral cortex postsynaptic density. The human gene has been mapped to chromosomal region 19q13.1. The gene is 11.8 kb long and contains 17 exons. APLP1 has been considered a candidate gene for CNF. All exon regions of the gene were amplified by the polymerase chain reaction and sequenced from DNA of CNF patients. No differences were observed between CNF patients and controls, suggesting that mutations in APLP1 are not involved in the etiology of CNF.

    Synonyms: AMYLOID BETA A4 PRECURSOR-LIKE PROTEIN 1 antibody|AMYLOID PRECURSOR-LIKE PROTEIN antibody| Amyloid-like protein 1 precursor antibody|APLP 1 antibody|APLP antibody|APLP-1 antibody| Aplp1 antibody|APLP1_HUMAN antibody|C30 antibody
    基因ID
    333
    UniProt
    P51693
    途径
    cAMP Metabolic Process
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