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PCSK6 抗体 (C-Term)

PCSK6 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043593
发货至: 中国
  • 抗原 See all PCSK6 抗体
    PCSK6 (Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))
    抗原表位
    • 8
    • 8
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 614-651, C-Term
    适用
    • 31
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 27
    • 3
    • 1
    克隆类型
    • 29
    • 2
    多克隆
    标记
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    This PCSK6 antibody is un-conjugated
    应用范围
    • 24
    • 23
    • 2
    • 1
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Proprotein convertase subtilisin/kexin type 6(PCSK6) detection. Tested with WB in Human,Rat.
    序列
    RNPEKQGKLK EWSLILYGTA EHPYHTFSAH QSRSRMLE
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Proprotein convertase subtilisin/kexin type 6(PCSK6) detection. Tested with WB in Human,Rat.
    Gene Name: proprotein convertase subtilisin/kexin type 6
    Protein Name: Proprotein convertase subtilisin/kexin type 6
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human PACE4 (614-651aa RNPEKQGKLKEWSLILYGTAEHPYHTFSAHQSRSRMLE), different from the related rat sequence by two amino acids.
    亚型
    IgG
    Top Product
    Discover our top product PCSK6 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    PCSK6 (Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))
    别名
    PCSK6 (PCSK6 产品)
    别名
    PACE4 antibody, PCSK6 antibody, SPC4 antibody, C86343 antibody, Pace4 antibody, Spc4 antibody, PACE4AIIa antibody, Xpace4 antibody, spc4 antibody, proprotein convertase subtilisin/kexin type 6 antibody, peptidase S8 antibody, proprotein convertase subtilisin/kexin type 6 L homeolog antibody, PCSK6 antibody, EAMY_RS27925 antibody, pcsk6 antibody, Pcsk6 antibody, pcsk6.L antibody
    背景
    Proprotein convertase subtilisin/kexin type 6 is an enzyme that in humans is encoded by the PCSK6 gene. This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. The encoded protease is constitutively secreted into the extracellular matrix and expressed in many tissues, including neuroendocrine, liver, gut, and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. Some of its substrates include transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression and left-right patterning. Alternatively spliced transcript variants encoding different isoforms have been identified.

    Synonyms: Paired basic amino acid cleaving enzyme 4 antibody|Paired basic amino acid cleaving system 4 antibody|PCSK6 antibody|PCSK6_HUMAN antibody|Proprotein convertase subtilisin/kexin type 6 antibody|SPC4 antibody|Subtilisin like protease antibody|Subtilisin-like proprotein convertase 4 antibody|subtilisin/kexin like protease PACE4 antibody|Subtilisin/kexin-like protease PACE4 antibody
    基因ID
    5046
    UniProt
    P29122
    途径
    Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
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