Neuroserpin 抗体 (C-Term)
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- 抗原 See all Neuroserpin (SERPINI1) 抗体
- Neuroserpin (SERPINI1) (serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1))
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抗原表位
- AA 272-310, C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Neuroserpin antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Neuroserpin(SERPINI1) detection. Tested with WB in Human,Mouse,Rat.
- 序列
- KAQLVEEWAN SVKKQKVEVY LPRFTVEQEI DLKDVLKA
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Neuroserpin(SERPINI1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: serpin peptidase inhibitor, clade I (neuroserpin), member 1
Protein Name: Neuroserpin - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Neuroserpin (272-310aa KAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKA L), different from the related mouse sequence by two amino acids, and from the related rat sequence by three amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product SERPINI1 Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- Neuroserpin (SERPINI1) (serpin Peptidase Inhibitor, Clade I (neuroserpin), Member 1 (SERPINI1))
- 别名
- SERPINI1 (SERPINI1 产品)
- 别名
- PI12 antibody, neuroserpin antibody, AI837402 antibody, Ns antibody, PI-12 antibody, Spi17 antibody, CG9453 antibody, Dmel\\CG9453 antibody, Serp2 antibody, Sp4 antibody, Spn4 antibody, Spn4A antibody, dSerp2 antibody, sp4 antibody, spn4 antibody, raPIT5a antibody, SERPINI1 antibody, pi12 antibody, serpini1l antibody, si:ch211-167c22.4 antibody, serpin family I member 1 antibody, serine (or cysteine) peptidase inhibitor, clade I, member 1 antibody, Serpin 42Da antibody, serpin peptidase inhibitor, clade I (neuroserpin), member 1 antibody, serpin family I member 1 L homeolog antibody, SERPINI1 antibody, Serpini1 antibody, Spn42Da antibody, serpini1 antibody, serpini1.L antibody
- 背景
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Neuroserpin is a protein that in humans is encoded by the SERPINI1 gene. This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Synonyms: DKFZp781N13156 antibody|Neuroserpin antibody|NEUS_HUMAN antibody|Peptidase inhibitor 12 antibody|PI-12 antibody|PI12 antibody|Protease inhibitor 12 antibody|Serine or cysteine proteinase inhibitor clade I (neuroserpin) member 1 antibody|Serine or cysteine proteinase inhibitor clade I member 1 antibody|Serpin I1 antibody|Serpin peptidase inhibitor clade I (neuroserpin) member 1 antibody|SERPINI1 antibody - 基因ID
- 5274
- UniProt
- Q99574
- 途径
- Regulation of Hormone Metabolic Process
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