-
- 抗原 See all CRTC2 抗体
- CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))
-
抗原表位
- AA 595-611, C-Term
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This CRTC2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for CREB-regulated transcription coactivator 2(CRTC2) detection. Tested with WB in Human.
- 序列
- QDPHTFNHQN LTHCSRH
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
-
Rabbit IgG polyclonal antibody for CREB-regulated transcription coactivator 2(CRTC2) detection. Tested with WB in Human.
Gene Name: CREB regulated transcription coactivator 2
Protein Name: CREB-regulated transcription coactivator 2 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human TORC2(595-611aa QDPHTFNHQNLTHCSRH), different from the related rat sequence by three amino acids, and from the related mouse sequence by two amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CRTC2 Primary Antibody
-
anti-CREB Regulated Transcription Coactivator 2 (CRTC2) (C-Term) antibody
Verified CRTC2 适用: 人, 大鼠 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 2 (CRTC2) antibodyCRTC2 适用: 人, 猴 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5B10 unconjugated
anti-CREB Regulated Transcription Coactivator 2 (CRTC2) (pSer171) antibodyCRTC2 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 2 (CRTC2) (AA 595-693) antibodyCRTC2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E6 unconjugated
anti-CREB Regulated Transcription Coactivator 2 (CRTC2) (AA 180-372) antibodyCRTC2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 2 (CRTC2) (AA 83-96) antibodyVerified CRTC2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 2 (CRTC2) (AA 595-693) antibodyCRTC2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 2 (CRTC2) (AA 542-553) antibodyVerified CRTC2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
-
- 应用备注
-
WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for CRTC2 is approximately 1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
-
At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - 有效期
- 12 months
-
- 抗原
- CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))
- 别名
- CRTC2 (CRTC2 产品)
- 别名
- CRTC2 antibody, TORC-2 antibody, TORC2 antibody, 4632407F12Rik antibody, Torc2 antibody, mTORC2 antibody, RGD1308903 antibody, CREB regulated transcription coactivator 2 antibody, CRTC2 antibody, Crtc2 antibody
- 背景
-
CRTC2(CREB-Regulated Transcription Coactivator 2), also known as TORC2, is a protein that in humans is encoded by the CRTC2 gene. The International Radiation Hybrid Mapping Consortium mapped the CRTC2 gene to chromosome 1. By cotransfection of TORC2 and reporter genes in HeLa cells, Iourgenko et al.(2003) found that TORC2 potently activated expression of genes driven by the IL8 promoter or a promoter carrying multiple CRE-like sequences. Liu et al.(2008) demonstrated that a fasting-inducible switch, consisting of the histone acetyltransferase p300 and the nutrient-sensing deacetylase sirtuin-1(SIRT1), maintains energy balance in mice through the sequential induction of CRTC2 and FOXO1. Using mice and primary mouse hepatocytes, Wang et al.(2009) found that Crtc2 functioned as a dual sensor for endoplasmic reticulum(ER) stress and fasting signals.
Synonyms: CREB regulated transcription coactivator 2 antibody|CREB-regulated transcription coactivator 2 antibody|CRTC2 antibody|CRTC2_HUMAN antibody|RP11-422P24.6 antibody|TORC-2 antibody|torc2 antibody|Transducer of CREB protein 2 antibody|Transducer of regulated cAMP response element-binding protein antibody|Transducer of regulated cAMP response element-binding protein(CREB) 2 antibody|Transducer of regulated cAMP response element-binding protein 2 antibody|Transducer of regulated CREB protein 2 antibody - 途径
- AMPK Signaling, Carbohydrate Homeostasis
-
You are here:
